Proteostasis Therapeutics, Inc. (NASDAQ:PTI) Files An 8-K Results of Operations and Financial Condition

Proteostasis Therapeutics, Inc. (NASDAQ:PTI) Files An 8-K Results of Operations and Financial Condition
Item 2.02.


PROTEOSTASIS THERAPEUTICS, INC. Exhibit
EX-99.1 2 d824733dex991.htm EX-99.1 EX-99.1 Exhibit 99.1   Proteostasis Therapeutics Reports Fourth Quarter and Year-End 2019 Financial Results and Provides Corporate Update BOSTON,…
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About Proteostasis Therapeutics, Inc. (NASDAQ:PTI)

Proteostasis Therapeutics, Inc. is a biopharmaceutical company. The Company is engaged in discovery and development of therapeutics that treat diseases caused by an imbalance in the proteostasis network, a set of pathways that control protein biosynthesis, folding, trafficking and clearance. It has developed the Disease Relevant Translation (DRT) technology platform, a drug screening approach for identifying highly translatable therapeutics based on predictive and functionally pertinent phenotypic assays and disease relevant models. Using this platform, it has identified a new class of small molecules, amplifiers that modulate proteins in the proteostasis network. It is developing and intend to commercialize its lead amplifier of CFTR protein, PTI-428, to improve CFTR protein function. It also focuses on developing PTI-NC-733, PTI-130, Usp14 program and unfolded protein response (UPR) program. PTI-130 is a small molecule amplifier.

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