Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Files An 8-K Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Files An 8-K Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year
Item 5.03

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AGIOS PHARMACEUTICALS INC Exhibit
EX-3.1 2 d653738dex31.htm EX-3.1 EX-3.1 Exhibit 3.1     SECOND AMENDED AND RESTATED BY-LAWS OF AGIOS PHARMACEUTICALS,…
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About Agios Pharmaceuticals, Inc. (NASDAQ:AGIO)

Agios Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is engaged in the discovery and development of orally available small molecule medicines for the treatment of cancer and rare genetic disorders (RGDs), which are a subset of orphan genetic metabolic diseases. Its cancer product candidates are AG-221 and AG-120, which targets mutated isocitrate dehydrogenase 2 and 1, or IDH2 and IDH1, respectively, and AG-881, which targets both mutated IDH1 and mutated IDH2. The lead product candidate in its RGD programs, AG-348, targets pyruvate kinase-R for the treatment of pyruvate kinase deficiency. Its AG-221 is an orally available, selective, inhibitor of the mutated IDH2 protein indicated for the treatment of patients with cancers. Its AG-120 is an orally available, selective, inhibitor of the mutated isocitrate dehydrogenase (IDH1) protein for the treatment of patients with cancers. AG-881 is an orally available, selective, brain-penetrant, pan-IDH mutant inhibitor.

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