On March 29, 2017, VistaGen Therapeutics, Inc. (the “Company”) announced that the European Patent Office has issued a Notice of Intention to Grant the Company’s European Patent Application for AV-101, the Company’s oral prodrug candidate in Phase 2 development for major depressive disorder. The granted claims covering multiple dosage forms of AV-101, treatment of depression and reduction of dyskinesias associated with L-DOPA treatment of Parkinson’s disease will be in effect until at least January 2034. A copy of the press release is attached to this Current Report on Form 8-K as Exhibit 99.1.

Item 9.01 Exhibits.

See Exhibit Index.

About VistaGen Therapeutics, Inc. (NASDAQ:VTGN)

VistaGen Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in developing and commercializing product candidates for patients with diseases and disorders involving the central nervous system (CNS). Its lead product candidate, AV-101, is an orally available prodrug candidate in Phase II development, initially for the adjunctive treatment of major depressive disorder (MDD) in patients with an inadequate response to standard antidepressants approved by the United States Food and Drug Administration (FDA). In addition to AV-101, the Company has developed a human pluripotent stem cell (hPSC) technology platform, which includes its in-vitro bioassay system, CardioSafe 3D, to predict potential heart toxicity of new chemical entities (NCEs) long before testing in animal and human studies. The Company is focused on regenerative medicine (RM) applications using blood, cartilage, heart and/or liver cells derived from hPSCs.

VistaGen Therapeutics, Inc. (NASDAQ:VTGN) Recent Trading Information

VistaGen Therapeutics, Inc. (NASDAQ:VTGN) closed its last trading session up +0.22 at 2.06 with 2,964 shares trading hands.