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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

  • Canopy Growth reported a CA$216 million loss amid board shake-ups.
  • Aurora Cannabis expanded presence in Australian medical cannabis market with MedReleaf acquisition.
  • Ayr Wellness strategically extended debt maturity and raised more capital.
  • Curaleaf expanded into Polish medical cannabis market with Can4Med acquisition.

Key Takeaways; Psychedelic Sector

  • Awakn’s phase III clinical trial for AWKN-001 recognized in psychedelic drug development pipeline bullseye chart.
  •  Clearmind expanded psychedelic portfolio with new Chinese patent approval.

Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends.

Top Marijuana Companies for Week

#1: Canopy Growth

Canadian cannabis giant Canopy Growth Corporation (NASDAQ: CGC) recently announced a series of significant developments alongside its third-quarter financial results. Despite reporting a lower net loss of CA$216.7 million compared to previous periods, the company’s revenue saw a decline, reflecting a challenging landscape in the cannabis industry.

The company reported a 7% decrease in total net revenue, amounting to CA$78.5 million for the third quarter of the fiscal year ending December 31, 2023. This decline was primarily attributed to lower Canadian cannabis sales, which dropped 16.3% year-over-year.

Additionally, the company reported a concerning challenge whereby the cash burn rate significantly reduced cash and cash equivalents to CA$142 million by the end of 2023.

One major highlight of the financial report was the board shake-up within Canopy Growth. The company disclosed changes to its board of directors, signaling a strategic shift in its leadership structure. Robert L. Hanson stepped down from the board, with Willy Kruh and Luc Mongeau appointed as new members. Both are expected to bring fresh perspectives to Canopy’s strategic direction.

The board adjustments coincide with Canopy’s intensified focus on its Canopy USA strategy, aimed at capitalizing on opportunities in the United States cannabis market. This strategy involves the creation of non-voting, non-participating exchangeable shares, a move subject to shareholder approval scheduled for April 12.

Looking ahead, Canopy Growth faces critical decisions regarding its financial sustainability. The company’s latest financial filing highlighted concerns about meeting short-term debt obligations and the need for additional financing to support its operations. Despite these challenges, CFO Judy Hong expressed confidence in Canopy’s ability to achieve sustained profitability and drive growth in the coming quarters.

#2: Aurora Cannabis

Aurora Cannabis Inc. (NASDAQ: ACB), a leading Canadian marijuana producer, acquired the remaining 90% equity interest of MedReleaf Australia, solidifying its presence in one of the largest federally regulated medical cannabis markets globally. The acquisition, which is valued at 50 million Australian dollars, signified Aurora’s strategic move to tap into the growing Australian market.

Australia’s medical cannabis sector has witnessed steady growth, positioning itself as one of the top two federally legal medical cannabis markets globally, alongside Canada. Aurora’s acquisition bolsters its foothold in both major markets, marking a significant milestone in the company’s expansion strategy.

Additionally, Aurora also announced its financial results for the quarter ended Dec. 31, 2023. In its financial report, the company reported a net loss of 25.2 million Canadian dollars, showcasing a 60% improvement compared to the same period the previous year.

Notably, medical cannabis sales for Aurora surged by 16% year-over-year, reaching CA$45.1 million in Q3, contributing to a total net revenue of CA$64.4 million. Despite encountering challenges in the recreational cannabis sector, with consumer cannabis net revenue dropping to CA$11.6 million, Aurora remains optimistic.

The company anticipates achieving positive free cash flow in the calendar year 2024 and emphasized its commitment to a debt-free status. As a result, the company announced plans to settle its remaining convertible debenture balance of approximately CA$7.3 million in late February. This financial stability will position Aurora uniquely in an industry where high debt loads and interest payments have significantly impacted profitability and flexibility.

#3: Ayr Wellness

Ayr Wellness Inc. (OTC: AYRWF), a prominent marijuana multistate operator (MSO), announced that it had successfully implemented measures to manage its significant debt. The company completed its plan to extend the maturity date of senior notes from 2024 to 2026, a move aimed at enhancing financial flexibility and long-term growth opportunities according to the company.

This maneuver is part of a broader plan by the company to manage its financial obligations, over the past year, Ayr Wellness has retired or extended the maturity of nearly $400 million in debt, signifying a proactive approach to financial management and stability.

To facilitate this restructuring, Ayr Wellness raised $40 million in new capital by issuing additional senior notes maturing in 2026. As a result, the company issued millions of subordinate voting shares to noteholders and shareholders, along with anti-dilutive warrants.

Moreover, Ayr Wellness announced the addition of Jared Cohen to its board of directors, pending necessary state cannabis regulatory approvals. Cohen’s expertise as a partner at FiSai Investments, is expected to enrich the company’s strategic vision and governance.

CEO David Goubert emphasized that these strategic actions are designed to position Ayr Wellness for sustained growth and enable the company to capitalize on favorable industry trends anticipated in the coming years. “These actions are designed to provide AYR with the flexibility to execute on its long-term growth strategy and take advantage of positive macro catalysts that are expected in the industry,” said David Goubert in a statement.

Ayr Wellness is scheduled to report its fourth-quarter and full-year earnings for 2023 on March 13, offering further insights into its financial performance and growth trajectory.

#4: Curaleaf

Curaleaf International, a London-based cannabis company and subsidiary of Curaleaf Holdings, Inc. (OTC: CURLF), made a significant move by acquiring Can4Med, a Polish medical cannabis operator headquartered in Wroclaw.

This acquisition marked Curaleaf’s entry into Poland, an emerging market for medical marijuana in Europe. Although the financial specifics of the deal were not disclosed, the strategic move underscores Curaleaf’s commitment to expanding patient access to medical cannabis products across the world.

Can4Med specializes in the acquisition, registration, and distribution of medical cannabis in Poland, making it an asset for Curaleaf International’s growth strategy. Curaleaf Holdings CEO, Matt Darin, emphasized the importance of this acquisition, stating that Poland’s medical cannabis market is experiencing rapid expansion, and partnering with Can4Med allows Curaleaf to better serve patients while driving growth across Europe.

According to Curaleaf, Poland distributed over 3,000 kilograms (3 metric tons) of medical cannabis in 2023, indicating a significant demand for such products in the country. In August, Curaleaf International achieved a milestone by registering its cannabis-based medicines as extracts in Poland through its local partner, CanPoland S.A.

Prior to the Can4Med acquisition, Curaleaf International had already secured registrations for its products in Malta and became the first company to register a THC-based cannabis extract active pharmaceutical ingredient in Italy. These achievements highlight Curaleaf’s position as a leader in expanding medical cannabis access throughout Europe.

Top Psychedelic Companies for Week

#1: Awakn

In the ever-evolving landscape of pharmaceuticals, particularly in the realm of mental health treatment, the emergence of psychedelics as potential therapeutics has garnered significant attention. Among the myriad of companies working in this space, Awakn Life Sciences Corp. (OTC: AWKNF) stands out with its pioneering efforts in addressing Severe Alcohol Use Disorder (SAUD) through its lead program, AWKN-001. Recently, Awakn’s Phase III clinical trial for AWKN-001 earned recognition in Psyched Alpha’s psychedelic drug development pipeline bullseye chart for year-end 2023, marking a significant milestone in the field of psychedelic medicine.

Severe Alcohol Use Disorder poses a substantial public health challenge globally, affecting millions of individuals and their families. Conventional treatment options for SAUD often fall short in providing sustainable outcomes, leaving a pressing need for more effective interventions. Recognizing this unmet medical need, Awakn Life Sciences embarked on a mission to harness the therapeutic potential of psychedelic compounds to address SAUD comprehensively.

The recognition of Awakn’s Phase III clinical trial in Psyched Alpha’s psychedelic drug development pipeline bullseye chart underscores the company’s dedication to advancing the field of psychedelic medicine and addressing critical unmet needs in mental health treatment.

#2: Clearmind

Clearmind Medicine Inc. (NASDAQ: CMND), a biotech company based in Tel Aviv, Israel, and Vancouver, Canada, recently secured patent approval in China for a novel psychedelic substance-based treatment targeting binge behaviors. The patent encompasses the use of a specific chemical compound, a primary amine aminoindan, to mitigate binge behaviors, extending beyond Clearmind’s proprietary molecule, 5-methoxy-2-aminoindan (MEAI).

MEAI, primarily developed to address alcohol use disorder, offers promise as a solution for individuals struggling with excessive alcohol consumption. Clearmind envisions its application extending to binge drinking, potentially providing relief for millions affected by this issue.

The approval marked a significant milestone in Clearmind’s strategy to establish intellectual property rights in the psychedelic-derived therapeutics field. With 27 patents already granted and 24 applications pending across multiple jurisdictions including the US, Europe, China, and India, the company is solidifying its position as a leader in psychedelic therapeutics research.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

  • High Tide reported record sales, as the company eyes expansion to Germany.
  • Cannara Biotech achieved record cannabis sales in first quarter.
  • Tilt Holdings aims to enhance the vape supply chain through debt restructuring with Smoore.
  • Aurora Cannabis is planning to consolidation its shares to regain Nasdaq compliance.

Key Takeaways; Psychedelic Sector

  • Numinus Wellness successfully raised $6 million in bought deal public offering.
  • Awakn successfully completed an investigative study that focused on advanced treatment for alcohol use disorder.

Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends.

Top Marijuana Companies for Week

#1: High Tide

High Tide Inc. (NASDAQ: HITI), a cannabis retailer and e-commerce platform operator based in Alberta, Canada, announced impressive financial performance for the 2023 fiscal year, ending in October. The company reported record sales of 487.7 million Canadian dollars ($362 million), marking a significant milestone in its growth trajectory. Despite this achievement, High Tide also disclosed a net loss of CA$41 million for the year, a substantial improvement from the previous year’s net loss of CA$71 million.

The company remains a dominant force in the Canadian cannabis market, boasting 163 store locations and serving 4.9 million customers across Canada, the United States, and Europe. High Tide’s CEO, Raj Grover, emphasized the company’s commitment to expanding its footprint both domestically and internationally. Grover highlighted the potential for international expansion, particularly in Germany, where the legalization of “cannabis clubs” and adult-use pilot projects could present lucrative opportunities for the company.

High Tide’s financial report also highlighted positive trends in free cash flow throughout the year, indicating improved operational efficiency and financial stability. The company reported a shift from negative cash flow in the first quarter to positive cash flow of CA$5.7 million in the final quarter.

Additionally, as of October 31, 2023, High Tide reported cash reserves of CA$30.1 million and gross debt of CA$28.8 million as of late January 2024, indicating a healthy financial position despite ongoing investment and expansion efforts.

With a positive outlook for the cannabis industry, fueled by regulatory advancements and growing consumer demand, High Tide remains optimistic about its prospects for continued growth and success in the global cannabis market.

#2: Cannara Biotech

Cannara Biotech Inc. (OTC: LOVFF), a leading cannabis producer headquartered in Montreal, announced record-breaking sales figures for the first quarter of fiscal year 2024. The company reported revenues of 19.5 million Canadian dollars ($14.6 million) for the three-month period ending on November 30.

This impressive figure represented an 89% surge compared to the CA$10.3 million recorded during the same period the previous year. Notably, Cannara Biotech’s net income for the September-November quarter amounted to CA$2.1 million, a significant leap from almost CA$3,000 in the first quarter of 2023.

Moreover, the company’s adjusted earnings before interest, taxes, depreciation, and amortization (EBITDA), a key profitability metric, soared to CA$5.2 million, marking a remarkable 206% year-over-year increase. Additionally, free cash flow for the quarter surged to CA$4.9 million, reflecting a substantial 145% rise compared to the previous year.

Additionally, Cannara Biotech disclosed a cash reserve of CA$2.6 million at the end of the quarter, emphasizing the company’s financial stability and liquidity.

The company’s robust infrastructure includes two expansive facilities in Quebec, spanning over 1.65 million square feet, with the capacity to yield approximately 100,000 kilograms (100 metric tons) of cannabis annually.

CEO Zohar Krivorot expressed excitement about the company’s upward trajectory, stating, “As we build on this momentum in 2024, our roadmap is clear, continued execution with excellence, cost efficiencies, and product innovation.”

#3: Tilt Holdings

Arizona-based marijuana vaporizer company TILT Holdings Inc. (OTC: TLLTF) recently restructured its debt with Smoore Technology Limited, aiming to bolster its vape supply chain and meet growing customer demands.

Under the agreement, which came into effect on January 28, Tilt’s subsidiary, Jupiter Research, received extended credit from Smoore, allowing Tilt to procure more CCell vape hardware products. Additionally, Smoore will maintain a first lien security interest in Tilt’s assets, therefore securing the credit line.

The restructuring involved Tilt guaranteeing the repayment of debts to Smoore, particularly for invoices overdue by more than 120 days. Sinosure, a Chinese export and credit insurance corporation, is expected to provide insurance coverage for the unpaid invoices beyond the 120-day mark.

Moreover, as part of the agreement, Tilt commited to reducing its outstanding balance with Smoore to $25 million by the end of 2024. According to the company, the repayment plan will prioritize settling invoices older than 150 days initially, and gradually address those over 120 days.

The restructuring with Smoore marks a strategic move for Tilt Holdings, ensuring a more robust vape supply chain amidst increasing market demands. Through collaborative efforts with Smoore and supportive noteholders, Tilt aims to enhance operational efficiency and sustain growth in the burgeoning marijuana vaporizer market.

#4: Aurora Cannabis

Canadian cannabis producer Aurora Cannabis Inc. (NASDAQ: ACB) announced plans to consolidate its shares in a bid to regain compliance with the Nasdaq’s minimum bid-price requirement. According to the company, this move is aimed at maintaining access to institutional investors and ensuring financial stability for the company.

The decision, which was approved by Aurora’s board of directors, will involve consolidating outstanding common shares at a ratio of one share for every 10 currently outstanding shares, subject to regulatory and stock exchange approvals. This action will significantly reduce the company’s outstanding shares from 475,903,822 to 47,590,382.

Aurora Cannabis anticipates the share consolidation to take effect around February 20th.

The Nasdaq requires listed equities to maintain a minimum bid price of $1. Falling below this threshold for 30 consecutive trading days renders a company deficient with the bid-price rule. Currently, Aurora’s shares are trading at $0.39 on the Nasdaq, necessitating prompt action to meet compliance standards.

Aurora joins several other cannabis companies on the Nasdaq’s list of noncompliant entities. These include Agrify Corporation (NASDAQ: AGFY), BYND Cannasoft Enterprises Inc. (NASDAQ: BCAN), Greenlane Holdings, Inc. (NASDAQ: GNLN), Hempacco Co., Inc. (NASDAQ: HPCO), IM Cannabis Corp. (NASDAQ: IMCC), and InMed Pharmaceuticals Inc. (NASDAQ: INM), each facing a compliance challenge from bid-price deficiency.

Top Psychedelic Companies for Week

#1: Numinus Wellness

Numinus Wellness Inc. (OTC: NUMIF), a mental health care company specializing in psychedelic-assisted therapies, successfully completed a bought deal public offering, raising $6 million. The company entered into an agreement with Eight Capital, representing a syndicate of underwriters, including co-lead underwriter and joint bookrunner Stifel GMP, to purchase 50,000,000 units at a price of $0.12 per unit.

The offering, which was conducted through a prospectus supplement to the company’s short-form base shelf prospectus, received lead orders from Integrated V.C., a venture fund committed to transforming global health and well-being, and the Multidisciplinary Association for Psychedelic Studies (MAPS), a non-profit organization specializing in psychedelic research and education.

Each unit comprises one common share and one common share purchase warrant, with the warrant exercisable at $0.18 per share for a 24-month period from the closing date of the offering. Additionally, Eight Capital holds an over-allotment option, allowing the purchase of up to 15% in additional units, potentially generating an additional $900,000 in proceeds.

The offering is expected to close on or about February 7, 2024, and is subject to regulatory and stock exchange approvals, including approval from the Toronto Stock Exchange. Numinus stated that it intends to utilize the proceeds for working capital and general corporate purposes as it continues to advance its mental health care initiatives.

#2: Awakn

Awakn Life Sciences Corp. (OTC: AWKNF) achieved a significant milestone in its quest to address Alcohol Use Disorder (AUD). In a recent announcement, the clinical-stage biotechnology company revealed the successful completion of an investigative study evaluating the dissociative effects of a proprietary S-ketamine oral thin film (OTF) formulation.

The study, which involved 28 participants classified as harmful drinkers, demonstrated the potential of Awakn’s S-ketamine OTF to induce dissociative effects, crucial for addiction treatment. The formulation proved well-tolerated with no serious adverse effects reported. Importantly, participants experienced a notable reduction in alcohol cravings compared to the placebo group.

This achievement followed Awakn’s strategic partnership with LTS Lohmann Therapie-Systeme AG, which granted Awakn global exclusivity for the use of its S-ketamine OTF in addiction, anxiety disorders, and eating disorders treatment.

Awakn designates this program as AWKN-002. And the company stated that this program, which combines the S-ketamine OTF with manualized relapse prevention cognitive-behavioral therapy (CBT) will target the US market for AUD treatment. This will complement the existing AWKN-001 program, which focuses on Severe AUD treatment in the UK market using intravenous racemic ketamine and manualized relapse prevention CBT.

Prof. Celia Morgan, the principal Investigator on the study, remarked on this significant milestone, “The rapid onset and offset of action of AWKN-002 and the ease of clinical use observed in our investigative study compared to IV ketamine has galvanized our view that this represents a way to dramatically widen access to ketamine treatment. AWKN-002 means that we may reach more of the patients that desperately need this life-saving addiction treatment”.

Looking ahead, Awakn plans to engage with the US Food and Drug Administration for a pre-IND meeting, marking a pivotal step towards advancing AWKN-002 through late-stage clinical trials.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

  • Planet 13 sold its marijuana license in Florida to facilitate expansion in the state; the company also announced plans to restate financials.
  • The Cannabist Co. initiated a $25 million debt buyback strategy.
  • Organigram shareholders overwhelmingly approved C$124M investment from British American Tobacco.

Key Takeaways; Psychedelic Sector

  • Awakn successfully completed an investigative study that focused on advanced treatment for alcohol use disorder.
  • FDA cleared Cybin for phase 2 DMT study.

Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends.

Top Marijuana Companies for Week

#1: Planet 13

Planet 13 Holdings Inc. (OTC: PLNH), a Nevada-based marijuana multistate operator, recently completed a strategic move to propel its expansion plans in Florida. The company successfully sold all shares of its subsidiary, Planet 13 Florida, to SGW FL Enterprises LLC, fetching a cash payment of $9 million in return. This transaction involved the transfer of a crucial medical marijuana treatment center (MMTC) license held by the Florida-based subsidiary.

The divestiture of the MMTC license was a crucial step for Planet 13 to advance its planned acquisition of VidaCann, a prominent medical marijuana company in Florida with extensive cultivation facilities and a robust retail network within the state’s medical market. The company stated that the $9 million obtained from the sale will play a pivotal role in facilitating the integration of VidaCann into Planet 13’s operations.

CEO Bob Groesbeck emphasized the significance of this strategic move in the company’s expansion strategy in Florida. “Part of the appeal of this deal is the amazing management team of VidaCann that has built it into the 9th largest Florida cannabis company with limited debt or outside capital. We believe their ability to run lean, efficient operations are a cultural and strategic fit with Planet 13’s company-wide philosophy and operations in other states,” commented Bob Groesbeck.

In a subsequent development, Planet 13 revealed its intention to restate certain financials. The company acknowledged the need to restate annual results for 2021 and 2022, along with quarterly results for the first three quarters of 2023. According to Planet 13, this decision arose from an internal investigation initiated by the company in November, which uncovered the misappropriation of $22 million of the company’s funds. The funds in question were held by the investment firm El Capitan Advisors.

#2: The Cannabist Co

The Cannabist Company Holdings Inc. (OTC: CBSTF), a prominent multistate operator in the marijuana industry, took a significant step towards financial restructuring by announcing a deal to repurchase up to $25 million in principal on senior secured debt through the issuance of shares.

The senior secured convertible notes, slated for maturity in June 2025, carry a 6% interest rate. The potential repurchases, amounting to $25 million, could involve the issuance of approximately 68.6 million shares, as disclosed by The Cannabist Co.

The debt repurchase plan, which was initially announced in September 2023, coincided with a $25 million private placement of units with the same institutional investors.

CEO David Hart expressed satisfaction with the agreement, stating, “We are pleased to have reached agreement on the previously announced transaction to reduce leverage and decrease interest expense, maintaining momentum for our balance sheet improvement plan.”

The Cannabist Co aims to fortify its financial position and build on its balance sheet improvement plan with this strategic move, this after the company has experienced some challenges in recent months. Notably, the company’s’ leadership underwent a change earlier this month, with David Hart taking over as CEO, succeeding co-founder Nick Vita. The company had also had a name change from Columbia Care in September 2023, a decision prompted by the collapse of Columbia Care’s planned mega-merger with Cresco Labs Inc. (OTC: CRLBF).

#3: Organigram

In a significant move that deepens British American Tobacco p.l.c. (NYSE: BTI) ties to the cannabis industry, Organigram Holdings Inc. (NASDAQ: OGI) received resounding approval from its shareholders for a C$124.6 million investment deal offered by a BAT subsidiary. The investment, finalized in a shareholder meeting on January 18, marked a pivotal moment for both companies.

With an overwhelming 96% approval rate, Organigram shareholders embraced the substantial investment from BAT, solidifying the tobacco giant’s financial stake in the Canadian cannabis operator. This investment underscores BAT’s strategic partnership with Organigram, which began Title: Organigram Shareholders Overwhelmingly Approve C$124M Investment from British American Tobacco

The investment deal, which closed last week, grants BAT a total equity of 45% in Organigram, coupled with a 30% ownership position in common voting shares. The funding infusion is expected to be a transformative force for Organigram, according to CEO Beena Goldenberg.

Organigram plans to utilize the capital to expand its international footprint and support additional research and development in the cannabis sector. Specifically, the company said that it will establish a “strategic investment pool” named Jupiter to efficiently deploy funds globally.

Top Psychedelic Companies for Week

#1: Awakn

Awakn Life Sciences Corp. (OTC: AWKNF) achieved a significant milestone in its quest to address Alcohol Use Disorder (AUD). In a recent announcement, the clinical-stage biotechnology company revealed the successful completion of an investigative study evaluating the dissociative effects of a proprietary S-ketamine oral thin film (OTF) formulation.

The study, which involved 28 participants classified as harmful drinkers, demonstrated the potential of Awakn’s S-ketamine OTF to induce dissociative effects, crucial for addiction treatment. The formulation proved well-tolerated with no serious adverse effects reported. Importantly, participants experienced a notable reduction in alcohol cravings compared to the placebo group.

This achievement followed Awakn’s strategic partnership with LTS Lohmann Therapie-Systeme AG, which granted Awakn global exclusivity for the use of its S-ketamine OTF in addiction, anxiety disorders, and eating disorders treatment.

Awakn designates this program as AWKN-002. And the company stated that this program, which combines the S-ketamine OTF with manualized relapse prevention cognitive-behavioral therapy (CBT) will target the US market for AUD treatment. This will complement the existing AWKN-001 program, which focuses on Severe AUD treatment in the UK market using intravenous racemic ketamine and manualized relapse prevention CBT.

Prof. Celia Morgan, the principal Investigator on the study, remarked on this significant milestone, “The rapid onset and offset of action of AWKN-002 and the ease of clinical use observed in our investigative study compared to IV ketamine has galvanized our view that this represents a way to dramatically widen access to ketamine treatment. AWKN-002 means that we may reach more of the patients that desperately need this life-saving addiction treatment”.

Looking ahead, Awakn plans to engage with the US Food and Drug Administration for a pre-IND meeting, marking a pivotal step towards advancing AWKN-002 through late-stage clinical trials.

#2: Cybin

Cybin Inc. (NYSE: CYBN), received clearance from the U.S. Food and Drug Administration (FDA) for its investigational new drug (IND) application for CYB004, a proprietary deuterated dimethyltryptamine (DMT) molecule. The clearance marked a significant milestone in Cybin’s efforts to develop innovative treatments for Generalized Anxiety Disorder (GAD).

The FDA’s approval allows Cybin to proceed with its Phase 2a study of CYB004, slated to commence in the first quarter of 2024. According to the company, this study will be a randomized, double-blind, active-controlled trial conducted at various sites across the United States. Its primary objective is to evaluate the preliminary clinical efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of CYB004 in individuals suffering from GAD.

With the FDA clearance and positive Phase 1 results, Cybin aims to advance the development of CYB004 as a potential therapeutic option for Generalized Anxiety Disorder. The company continues to explore the safety and efficacy of deuterated DMT molecules, with a focus on addressing mental health conditions such as anxiety and depression.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

  • Tilray narrowed loss to $46 million in Q2 2024 amid record sales.
  • Canopy Growth’s financial struggles prompted a $30 million equity raise through private placement.
  • Cannabis MSO 4Front Ventures converted debt to equity and welcomed new CEO.

Key Takeaways; Psychedelic Sector

  • PharmaTher is anticipating FDA approval for ketamine treatment in April 2024.
  • Awakn’s AWKN-P001 advanced to phase III after promising phase II a/b trial results.

Two weeks into the new year, the cannabis sector is buzzing with anticipation as a recent unredacted exchange among federal authorities revealed a compelling catalyst for a potential rally. The released documents from the Health and Human Services disclosed that federal scientists are recommending the removal of marijuana from the Schedule One drug classification. Their argument contends that cannabis is less risky and has a lower potential for abuse compared to other Schedule One substances like heroin. The letter also highlighted significant changes since the last DEA consideration in 2015, including congressional adjustments to cannabis classification and notable medical advancements. With pressure mounting on the DEA to acknowledge these findings, the sector stands on the brink of a potential resurgence.

Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends.

Top Marijuana Companies for Week

#1: Tilray

Canadian cannabis producer Tilray Brands, Inc. (NASDAQ: TLRY) reported a reduced loss of $46.2 million in the second quarter of the fiscal year 2024, thanks to a surge in net sales. The company’s Q2 revenue reached $193.8 million, marking a 34.4% year-over-year (YoY) improvement and meeting analyst expectations.

All key operating segments, including cannabis, distribution, wellness, and beverage alcohol, contributed to the revenue growth.

Cannabis sales saw a significant increase, reaching $67.1 million compared to $49.9 million in the same quarter the previous year. The distribution business experienced a 12% YoY revenue jump to $67.2 million. The wellness business saw a modest 2.2% increase to $12.9 million, while net revenue in the beverage alcohol segment more than doubled to $46.5 million; As a result, Tilray is now the fifth-largest craft beer brewer in the U.S., according to the company.

The adjusted EBITDA for Q2 was $10.1 million, slightly lower than the previous year. Tilray said that they are aiming for an adjusted EBITDA target of $68 million to $78 million for the fiscal year ending in May 2024 and expects positive adjusted free cash flow.

However, the company revised its adjusted free cash flow definition, excluding integration costs from the September 2023 acquisition of eight beer and beverage brands. Adjusted free cash flow for the second quarter was negative $18.4 million, while free cash flow without adjustments was negative $36.2 million. As of November 30, Tilray’s cash and cash equivalents amounted to $143.4 million

Tilray’s CEO, Irwin Simon, highlighted the company’s revenue growth, capital structure enhancement, and operational synergies, reaffirming its position as a leading cannabis operation in Canada and Europe; “We grew revenue, enhanced our capital structure, and realized operating synergies while strengthening Tilray Brands’ position as the #1 cannabis operation and brand portfolio in Canada by sales volume and market share, the European market leader in medical cannabis, and the leader in branded hemp products,” Irwin Simon said in the press statement.

#2: Canopy Growth

Canadian cannabis company Canopy Growth Corporation (NASDAQ: CGC), which has been facing financial challenges, decided to raise $30 million through a private placement of shares and warrants. The troubled company sold close to 7 million units at a price of $4.29 each. Each unit was comprised of either one Canopy share and a warrant to buy another share at $4.83, exercisable for five years immediately after the offering closes, or one share with a warrant exercisable starting six months after closing.

According to the company, the funds generated from this equity sale will be utilized to pay down debt as part of Canopy’s overall strategy for debt reduction, working capital, and other general corporate purposes. The private placement involved unspecified institutional investors and was expected to conclude on January 10.

Canopy Growth experienced a decline in share value following this announcement. The company, which is based in Smiths Falls, Ontario, has been navigating financial challenges and restructuring efforts. Notable actions include closing its flagship facility and downsizing in February 2023, divesting its BioSteel subsidiary in November, and selling its This Works skin care unit in December.

Despite these measures, Canopy Growth reported a significant annual loss of 3.3 billion Canadian dollars ($2.5 billion) for its preceding fiscal year. The company, which is eager to enter the U.S. marijuana market, previously engaged in a private placement of shares and warrants in September. Additionally, Canopy recently consolidated its shares to maintain its Nasdaq listing. The capital raised from the current private placement is no doubt crucial for the company’s ongoing efforts to stabilize its financial position and pursue strategic objectives.

#3: 4Front Ventures

In a strategic financial move, 4Front Ventures Corp. (OTC: FFNTF), a multistate cannabis operator headquartered in Phoenix, Arizona, successfully converted $23 million of its senior secured debt into equity. This transformation saw approximately 44% of the debt being changed into subordinate voting shares at a rate of 0.125 Canadian dollars ($0.094) per share.

The company also introduced 15% warrant coverage with an exercise price of CA$0.144, allowing each warrant to be exercisable for one subordinate voting share over a three-year period. The remaining $28.7 million of the loan remained unaltered, carrying a 12% interest rate. The approval process for this amendment is currently underway.

In conjunction with this financial restructuring, 4Front Ventures announced the appointment of Andrew Thut as its new CEO, effective January 8. Andrew Thut, who previously served as the company’s CFO and chief investment officer, succeeds Leo Gontmakher, the former CEO who served since May 30, 2020. While Gontmakher steps down from the CEO role, 4Front said he would continue to contribute to the company as a member of the board of directors.

The decision to convert a significant portion of the debt into equity and the leadership change signify 4Front’s commitment to optimizing its balance sheet, ensuring the financial stability of the company, and aligning its focus on long-term growth opportunities.

Top Psychedelic Companies for Week

#1: PharmaTher

Toronto-based PharmaTher Holdings Ltd. (OTC: PHRRF) announced that they are anticipating full approval from the U.S. Food and Drug Administration (FDA) in April for its ketamine-based treatment, KETARX. Initially developed for Parkinson’s Disease, the drug is poised to address a broader range of conditions, including pain, mental health, and neurological disorders.

The FDA had set an approval goal date of April 29, 2024, which PharmaTher confirmed remains on track. In the event of FDA approval, the company plans to resume a comprehensive portfolio targeting various ailments, aiming to alleviate a national ketamine shortage, seek international approvals, and continue research and development.

PharmaTher is confident in the approval and is reallocating funds for U.S. commercial scale-up and global regulatory approvals. Post-approval, KETARX production will begin in the U.S. and extend to Canada, addressing a ketamine shortage since February 2023. PharmaTher anticipates a transformative 2024, with potential restarts of paused clinical programs in the latter half of the year. The company is optimistic about ketamine’s therapeutic potential, citing positive results in mental health disorders based on recent studies.

#2: Awakn

Awakn Life Sciences Corp. (OTC: AWKNF) successfully completed a Phase II a/b clinical trial for AWKN-P001, a groundbreaking therapeutic aimed at treating Severe Alcohol Use Disorder (SAUD). AWKN-P001 combines the use of racemic ketamine, administered intravenously, with carefully designed psycho-social support to address the challenges of SAUD.

When coupled with therapy, Awakn’s innovative approach has demonstrated a significant reduction in the likelihood of relapse in Alcohol Use Disorder patients. The Phase II a/b trial results revealed remarkable success, with participants in the active arm achieving an 86% abstinence rate at 6 months post-treatment. This marked a stark contrast to the 2% abstinence rate observed pre-trial and the 25% rate seen with the current standard of care for SAUD.

AWKN-P001’s development aims to establish a licensed therapeutic for SAUD and set a regulatory precedent for combining drugs with psycho-social support to treat addiction. The therapy has already progressed to Phase III, having received regulatory and ethical approval in the second half of 2023. Awakn has secured a grant from the UK Department for most of the the Phase III trial’s costs, with the company’s expenses capped at approximately US$1 million.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

  • Village Farms expanded Canadian cannabis brands into growing UK market.
  • Agrify reported improved performance in the Q3 2023 financial results.
  • Trulieve secured a $25 million loan and welcomed a new CFO.

Key Takeaways; Psychedelic Sector

  • Awakn’s AWKN-P001 advanced to phase III after promising phase II a/b trial results
  • Atai invested $50 million in Beckley Psytech to accelerate development of rapid-acting psychedelic medicines.

This week was the inaugural week of 2024, a year poised to be a dynamic rollercoaster of highs and lows in the ever-evolving landscape of the cannabis and psychedelic sectors. As we step into the unknown, anticipation runs high, especially in the cannabis sector, where investors eagerly await potential shifts in marijuana regulations, hinting at rescheduling and the elusive promise of federal legalization. Simultaneously, the psychedelic realm is breaking barriers and going mainstream, emerging as a potential solution for various underlying medical conditions.

Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends. Make sure you join us throughout the year as we report on the unfolding events in these sectors—how they transpire, why they matter, and the profound impacts they carry.

Top Marijuana Companies for Week

#1: Village Farms

Village Farms International, Inc. (NASDAQ: VFF), based in Vancouver, British Columbia, successfully launched its premier cannabis brands, Pure Sunfarms, and The Original Fraser Valley Weed Co., in the United Kingdom (UK). This marked the company’s entry into its fourth overseas medical cannabis market, with the products being distributed by 4C Labs, a leading UK medical cannabis company. The move comes as part of the company’s broader strategy to tap into the rapidly growing international market for medical cannabis.

The UK market has witnessed substantial growth, particularly since the government’s decision to allow bulk imports in 2020. Village Farms’ entry into the UK market signifies a significant milestone in its global expansion efforts. Through its subsidiary, Pure Sunfarms, the company is now exporting its preferred Canadian-grown cannabis products to various international destinations, including Germany, Australia, Israel, and the UK, collectively representing a population of over 185 million.

Village Farms CEO Michael DeGiglio expressed enthusiasm about the launch, stating, “This launch of our leading BC-grown cannabis brands is a game-changer for patients in the UK, the third most populated country in Europe.” DeGiglio further emphasized the company’s success in international markets and its commitment to delivering high-quality products.

Greg Dobbin, President, and CEO of 4C Labs, the distribution partner in the UK, also expressed confidence in Village Farms’ products resonating with UK consumers. Dobbin stated, “Village Farms is known to be the best in the world at delivering such quality, with stable supply, and we are confident these brands will resonate with UK consumers immediately upon launch.”

The UK shipment marks a pivotal moment for Village Farms, contributing to its fast-growing international sales segment. For the nine months ending September 30, 2023, the company reported international sales of 5.1 million Canadian dollars, a significant increase from the previous year’s 1.9 million. As the UK medical cannabis market continues to expand, Village Farms aims to establish a dominant position, building on its success in Canada and other international markets.

#2: Agrify

Agrify Corporation (NASDAQ: AGFY), a leading provider of innovative cultivation and extraction solutions for the cannabis industry, recently announced its financial results for the third quarter ending September 30, 2023. Despite a decline in revenue, the company reported a significant reduction in net losses and highlighted successful cost-cutting measures that led to the “lowest historical net loss” since its inception.

For the third quarter of 2023, Agrify reported a revenue of $3.1 million, down from $7 million in the same period in 2022. However, the gross profit improved to $1 million compared to a loss of $4.1 million in the third quarter of 2022. The net loss attributable to Agrify stood at $2.1 million, a substantial improvement from the net loss of $57.4 million in the same quarter of the previous year.

Despite these improvements, Agrify acknowledged liquidity concerns, reporting only $200,000 in cash, cash equivalents, and marketable securities as of September 30, 2023.

Raymond Chang, Chairman and CEO of Agrify, expressed satisfaction with the company’s various initiatives, stating, “The historically low net loss of $2.1 million is encouraging and good evidence that we are moving in the right direction. The team remains committed to turning the business profitable in the shortest time possible.”

Agrify’s Q3 2023 financial results indicate a positive shift in its performance, driven by effective cost-cutting measures and strategic decisions. Despite revenue challenges, the company’s focus on reducing losses and improving gross profit is noteworthy. However, it remains crucial for Agrify to address liquidity concerns and navigate the competitive landscape as it works towards achieving profitability.

#3: Trulieve

Florida-based Trulieve Cannabis Corp. (OTC: TCNNF) recently finalized a significant financial move, securing a new commercial loan of $25 million at an 8.31% interest rate for a five-year term. This strategic financial maneuver aims to support the company’s ongoing operations and enhance its cash position.

Trulieve utilized one of its Florida cannabis cultivation sites as collateral for the loan, with First Federal Bank acting as the lead agent in the deal. This move is seen as a means to provide the company with greater flexibility as it prepares for growth catalysts in the dynamic cannabis industry.

Kim Rivers, Trulieve CEO, highlighted the importance of the loan in a statement, stating, “This loan provides Trulieve greater flexibility and bolsters our cash position as we focus on preparing for growth catalysts.” John Medina, CEO of First Federal Bank, emphasized the significance of the cannabis industry in Florida, describing it as “an important and complex sector with a significant presence.”

In addition to the financial developments, Trulieve also announced the appointment of Wes Getman as the new Chief Financial Officer (CFO), effective January 1. Getman brings 25 years of experience in accounting and finance, having worked with notable companies such as Blue Bird Corp., Grant Thornton, and PricewaterhouseCoopers. Prior to joining Trulieve, he served as a partner at business management consultancy WilliamsMarston.

Top Psychedelic Companies for Week

#1: Awakn

Awakn Life Sciences Corp. (OTC: AWKNF) successfully completed a Phase II a/b clinical trial for AWKN-P001, a groundbreaking therapeutic aimed at treating Severe Alcohol Use Disorder (SAUD). AWKN-P001 combines the use of racemic ketamine, administered intravenously, with carefully designed psycho-social support to address the challenges of SAUD.

When coupled with therapy, Awakn’s innovative approach has demonstrated a significant reduction in the likelihood of relapse in Alcohol Use Disorder patients. The Phase II a/b trial results revealed remarkable success, with participants in the active arm achieving an 86% abstinence rate at 6 months post-treatment. This marked a stark contrast to the 2% abstinence rate observed pre-trial and the 25% rate seen with the current standard of care for SAUD.

AWKN-P001’s development aims to establish a licensed therapeutic for SAUD and set a regulatory precedent for combining drugs with psycho-social support to treat addiction. The therapy has already progressed to Phase III, having received regulatory and ethical approval in the second half of 2023. Awakn has secured a grant from the UK Department for most of the the Phase III trial’s costs, with the company’s expenses capped at approximately US$1 million.

#2: Atai

Atai Life Sciences N.V. (NASDAQ: ATAI), a psychedelic biotech company, made a substantial investment of $50 million in Beckley Psytech Limited, a clinical-stage biotechnology company focusing on transforming short-duration psychedelics into fast-acting medicines for neuropsychiatric conditions. The investment comprises a $40 million direct investment for ongoing research and an additional $10 million to acquire shares from existing shareholders.

Atai’s investment will grant them a 35.5% ownership stake in Beckley Psytech, with additional rights such as 1:1 warrant coverage, the ability to appoint and hold three seats on the Board of Directors, and a time-limited right of first refusal on future sales or transfers of commercial rights.

Atai’s CEO, Florian Brand, emphasized the diversity of their drug candidates, recognizing the individuality of neuropsychiatric patient populations; “When it comes to mental health, there is no one-size-fits-all solution, and the diverse pharmacology of our drug candidates acknowledges the heterogeneity of neuropsychiatric patient populations. Looking ahead to the next 12 months, adding to our already strong pipeline of potential catalysts, we anticipate this investment will lead to several additional meaningful clinical readouts, including topline results from the BPL-003 Phase 2b study, expected in the second half of 2024,” Florian Brand said in the press statement.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

• Canopy Growth implemented share consolidation to meet Nasdaq listing standards.
• Curaleaf successfully listed on the Toronto Stock Exchange.
• Safe Harbor Financial boosted social equity in Connecticut with a $1.17m loan to Higher Collective.
Key Takeaways; Psychedelic Sector
• Awakn achieved significant regulatory milestone and closed financing tranche as per the recent corporate update.
• MindMed reported positive results for Phase 2b trial in generalized anxiety disorder.
Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends.
Top Marijuana Companies for Week

#1: Canopy Growth
Canopy Growth Corporation (NASDAQ: CGC), a prominent Canadian cannabis producer, announced a share consolidation strategy to maintain its listing on the Nasdaq exchange. The decision, which was approved during the company’s annual general meeting in September, entailed consolidating shares at a ratio of one post-consolidation common share for every ten pre-consolidation shares. The move aims to bring Canopy’s share price in line with Nasdaq’s minimum bid requirement of $1 per share.
The consolidation plan became effective on Friday, December 15, with post-consolidation shares expected to commence trading on both the Nasdaq (CGC) and the Toronto Stock Exchange (WEED) on Monday, December 20.
Canopy’s Chief Financial Officer, Judy Hong, stated that the share consolidation is expected to help the company regain compliance with Nasdaq’s bid requirement and enhance the marketability of its shares; “By implementing this share consolidation, Canopy Growth expects to regain compliance with the Nasdaq’s bid requirement and further support the marketability of the Company’s shares,” Judy Hong said in the press release.
Canopy Growth joins the ranks of other Nasdaq-listed cannabis companies, including Hexo Corp. (now part of Tilray Brands, Inc. (NASDAQ: TLRY)), Organigram Holdings Inc. (NASDAQ: OGI), and Agrify Corporation (NASDAQ: AGFY), that have previously implemented share consolidations to meet Nasdaq listing standards.

#2: Curaleaf
New York-based marijuana multistate operator, Curaleaf Holdings, Inc. (OTC: CURLF), successfully commenced trading on the Toronto Stock Exchange (TSX) on Thursday, marking a significant move for the company. The shares of Curaleaf are now listed as CURA on the Canadian exchange.
Curaleaf’s senior management team, led by CEO Matt Darin and Executive Chair Boris Jordan, had the honor of ringing the opening bell at the TSX on Thursday. The decision to list on the TSX came after the company received conditional approval the week before.
The transition to the TSX also involved the delisting of Curaleaf’s shares from the Canadian Securities Exchange, which was completed at the close of markets on Wednesday. Shareholders were assured that no action on their part was required in this process.
The decision to list on the TSX mirrored a trend within the marijuana industry, with fellow multistate operator TerrAscend Corp. (OTC: TSNDF) making a similar move in July. Both companies sought to tap into a larger pool of investors available on the TSX, aiming for increased visibility and access to institutional support.
Curaleaf’s uplisting represents the company with a significant step in aligning with broader market trends and expanding its reach within the investment landscape. And Boris Jordan expressed confidence in the company’s direction following the listing, stating, “I am as confident as ever in the direction we are headed, and I am grateful to the TSX, our shareholders, partners, and everyone in the company for helping get us here today.”

#3: Safe Harbor Financial
In a significant move to support social equity initiatives in the emerging Connecticut cannabis market, SHF(Safe Harbor Financial) Holdings, Inc. (NASDAQ: SHFS), a leading cannabis industry financial services firm, along with its partners announced a $1.17 million loan to a prospective marijuana retailer in the state. The forthcoming marijuana retailer store, Higher Collective brand, is set to become a flagship social equity joint venture, signaling a positive step towards inclusive growth within the cannabis industry.
The substantial $1.17m loan, aimed at acquiring and constructing the new store, is backed by a first lien on the property. While specific details such as the loan’s term and interest rate were not disclosed by Colorado-based Safe Harbor, the financial services firm emphasized that the debt was issued at market-competitive terms. Notably, these terms include a flexible structure allowing interest-only payments during the construction period.
Higher Collective, with its existing portfolio of four adult-use retail stores in Connecticut, is rapidly expanding its footprint in the state. Dan Roda, Executive Vice President, and Chief Operating Officer of Safe Harbor expressed the firm’s satisfaction in supporting this growing social equity joint venture. He stated, “We are pleased to support this rapidly growing social equity joint venture, which aligns with Safe Harbor’s commitment to supporting social equity operators within the cannabis industry with the provision of normalized banking services.”

Top Psychedelic Companies for Week

#1: Awakn
Awakn Life Sciences Corp. (OTC: AWKNF), a clinical-stage biotechnology company specializing in addiction therapeutics, provided a corporate update highlighting recent milestones and financial developments.
The first noteworthy achievement involved the company receiving regulatory and ethical approvals for the phase III clinical trial of its lead program, AWKN-P001, which is designed to address Severe Alcohol Use Disorder (SAUD). This collaborative trial, funded by both Awakn and the NIHR Efficacy and Mechanism Evaluation (EME) Programme, was authorized by the Medicines and Healthcare products Regulatory Agency (MHRA) and received ethical approval from the UK’s Health Research Authority.
In addition, Awakn completed a feasibility study for its MDMA proprietary formulation using Catalent’s Zydis® orally disintegrating tablet (ODT) technology. The study confirmed the stability of MDMA on Zydis ODT technology, indicating its suitability for pre-gastric absorption.
Awakn also engaged Orphan Insight Ltd. to spearhead the development and advancement of market access, pricing, and reimbursement strategies for its lead program, AWKN-P001.
On the financial front, Awakn initiated a non-brokered private placement financing on April 26, 2023, with an initial target of $3,000,000 in gross proceeds. Subsequently, the offering was upsized to $4,000,000 on June 15, 2023, at a price of CAD$0.46 per unit. Each unit comprises one common share and three-quarters of one whole common share purchase warrant.
As of the recent update, Awakn said that they had closed the fourth tranche of the private placement, issued 500,000 units, and raised gross proceeds of $230,000 for this tranche. In total, the company stated that they had raised $2,964,663 through the offering as of Friday, December 15, 2023. The company also said that they intend to use the gross proceeds from the offering to fund the company’s general working capital.

#2: MindMed
Mind Medicine (MindMed) Inc. (NASDAQ: MNMD) reported positive topline results from its Phase 2b clinical trial of MM-120 (lysergide d-tartrate) in treating generalized anxiety disorder (GAD). The trial successfully met its primary endpoint, demonstrating statistically significant and clinically meaningful dose-dependent improvements on the Hamilton Anxiety rating scale (HAM-A) compared to a placebo at Week 4. MM-120 was administered as a single dose in a monitored clinical setting without additional therapeutic intervention.
Robert Barrow, CEO and Director of MindMed, expressed excitement over the positive results, emphasizing the potential impact on patients affected by GAD; “We are excited by the strong positive results for MM-120 in GAD, particularly given that this is the first study to assess the standalone drug effects of MM-120 in the absence of any psychotherapeutic intervention. These promising findings represent a major step forward in our goal to bring a paradigm-shifting treatment to the millions of patients who are profoundly impacted by GAD,” said Robert Barrow.
With approximately 20 million people currently suffering from GAD—a condition associated with underdiagnosis and underservice—these findings mark a crucial step forward. MindMed said that they plan to share additional study results in the coming months, including topline 12-week results in the first quarter of 2024. The company also stated that they aim to collaborate closely with the FDA to finalize the Phase 3 development program for MM-120 in GAD.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

• The Cannabist Company celebrated approval for adult-use cannabis sales in New York.
• Curaleaf gained conditional approval for uplisting to the Toronto Stock Exchange.
• MedMen prevailed in legal battle against Whitestar Solutions allegations.
Key Takeaways; Psychedelic Sector
• Awakn received regulatory and ethical approval for Phase III clinical trial of AWKN-P001.
• Filament Health secured $4.3 million financing, as they advance Nasdaq uplisting efforts.

In a dynamic week for the cannabis sector, New York state regulators granted approval to six Cannabis multistate operators with medical marijuana licenses to enter the adult-use market on December 29, marking a pivotal moment one year after the launch of recreational sales. This widely anticipated decision signified a significant milestone in the state’s recreational marijuana market rollout, and it follows the New York State Supreme Court’s recent decision to lift an injunction on December 1, enabling the issuance of new adult-use business licenses.
The six operators that got the green light from the state’s Cannabis Control Board include: Curaleaf NY, part of New York-headquartered MSO Curaleaf Holdings, Inc. (OTC: CURLF), Valley Agriceuticals LLC, which is owned by Cresco Labs Inc. (OTC: CRLBF), NYCanna, part of New York-headquartered MSO Acreage Holdings, Inc. (OTC: ACRHF), Columbia Care NY, whose parent is New York-based MSO The Cannabist Company Holdings Inc. (OTC: CBSTF), Etain Health, owned by RIV Capital Inc. (OTC: CNPOF), a Toronto-based investment firm, and PharmaCann, whose parent is Chicago-based private MSO PharmaCann.
Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends.
Top Marijuana Companies for Week

#1: The Cannabist Company
The Cannabist Company Holdings Inc. (OTC: CBSTF), formerly known as Columbia Care, celebrated a significant milestone as it received approval from the New York Office of Cannabis Management for adult-use wholesale distribution and retail sales. As a result, the company stated that they will immediately commence adult-use wholesale deliveries in New York, offering products from its Riverhead and Rochester cultivation facilities to active retail locations across the state.
The Cannabist Company, which is a prominent cultivator, manufacturer, and retailer of cannabis products in the U.S., said that they plan to make their popular brands, including Seed & Strain and Hedy edibles, available to both existing and newly approved adult-use dispensaries. According to the company, the first sale is set to take place with Herbal IQ, a retailer with five locations near Buffalo and Rochester. The company also anticipates launching additional brands in the coming months, subject to regulatory approval.
Nicholas Vita, CEO of The Cannabist Company, expressed excitement about the approval to enter the adult-use market in New York, citing the state as the “cannabis capital of the East Coast.” Vita emphasized the company’s readiness to meet the growing demand by leveraging its scaled cultivation and manufacturing facilities in Long Island and Rochester.
“After more than a decade of serving the New York medical market, the day has finally arrived for us to capitalize on the tremendous assets we have built and to begin bringing trusted, tested products to the growing adult-use market. New York is the cannabis capital of the East Coast, and we are thrilled to be supplying our partners with high-quality products as the industry reaches a new milestone with the further implementation of adult-use sales,” said Nicholas Vita.

#2: Curaleaf
New York-based cannabis multistate operator Curaleaf Holdings, Inc. (OTC: CURLF) achieved a significant milestone in its strategic plan of securing “conditional approval” from Canadian securities regulators to uplist its shares to the prestigious Toronto Stock Exchange (TSX), which is the third-largest stock exchange in North America. The move, which was announced on December 7, 2023, reflects Curaleaf’s ongoing efforts to broaden its investor base and enhance its financial standing.
The uplisting, which will involve the trading of subordinate voting shares, is not yet finalized, as Curaleaf must fulfill certain conditions set by the TSX before its shares can officially begin trading on the exchange. The company affirmed that it would issue another statement once this process is complete, providing clarity on the timeline for its shares becoming active on the TSX.
As part of the transition, Curaleaf will cease trading on the Canadian Securities Exchange (CSE), where it is currently listed under the symbol CURA. The company intends to be delisted from the CSE as soon as its shares are officially listed on the TSX.
The decision to uplist follows the application made by Curaleaf in October, a strategic move that mirrors the trajectory of other multistate operators like TerrAscend Corp. (OTC: TSNDF), which successfully transitioned to the TSX in July. Uplistings such as these are part of a broader industry trend aimed at accessing a wider pool of investors and capitalizing on the increased liquidity associated with major stock exchanges.

#3: MedMen
MedMen Enterprises Inc. (OTC: MMNFF) secured a legal victory in a case filed by Whitestar Solutions LLC, where Whitestar accused MedMen of fraudulent inducement in a breach-of-contract lawsuit. The dispute originated in 2020 when Whitestar alleged that MedMen had misrepresented stocks used in the acquisition of EBA Holdings Inc., a cannabis cultivation and dispensary business in Arizona.
Whitestar claimed that it agreed to an all-stock deal, expecting unrestricted stock, but later discovered that the stocks were encumbered as they were foreign-issued shares subject to restrictive legends. Despite this revelation, Whitestar proceeded with the deal, leading to complications later.
The Arizona Court of Appeals recently upheld the initial decision in favor of MedMen, rejecting Whitestar’s arguments. The court determined that Whitestar failed to provide evidence of harm or damage caused by the alleged misrepresentation.
This legal victory is significant for MedMen, a cannabis multistate operator based in Los Angeles, as it reinforces the company’s position against allegations of fraudulent practices and breaches of contract.
Top Psychedelic Companies for Week

#1: Awakn
Awakn Life Sciences Corp. (OTC: AWKNF), a pioneering clinical-stage biotechnology company, recently achieved a significant milestone in the development of its lead program, AWKN-P001, designed to revolutionize the treatment of Severe Alcohol Use Disorder (SAUD). The company announced the receipt of clinical trial authorization from the Medicines and Healthcare products Regulatory Agency (MHRA) and ethical approval from the Health Research Authority in the UK for a phase III clinical trial.
SAUD, the most acute form of alcohol use disorder, affects approximately 12.5 million individuals in the US and key European markets, including Germany, the UK, France, Italy, and Spain.
AWKN-P001 represents a novel therapeutic approach, combining a N-methyl-D-aspartate receptor-modulating drug (ketamine) with psycho-social support to address SAUD. The results from the phase II study were highly promising, demonstrating an 86% abstinence rate in the six months post-treatment, a stark contrast to the mere 2% abstinence rate pre-trial. Additionally, AWKN-P001 showed a 25% abstinence rate, surpassing the current standard of care.
The phase III trial, funded by Awakn, The University of Exeter, and a partnership between the National Institute for Health and Care Research (NIHR) and the Medical Research Council (MRC), will involve 280 participants in a two-armed randomized placebo-controlled trial.
Anthony Tennyson, Awakn CEO, highlighted the significance of the regulatory and ethical approval: “This regulatory and ethical approval is not only a testament to our commitment to scientific rigor and patient well-being, but also a pivotal step in our commercial journey. It opens new horizons for Awakn, as we move one step closer to delivering a potentially transformative therapy to the market.”

#2: Filament Health
Vancouver-based psychedelic drug development company, Filament Health Corp. (OTC: FLHLF), successfully secured $4.3 million in financing, with an option to obtain an additional $11.1 million, through a securities purchase agreement with Helena Global Investment Opportunities 1 Ltd. The funding comes in the form of secured convertible notes, with a 10% annual interest rate and a 12-month term. Filament said that they plan to use the funds to support its ongoing operations and drug development programs.
The financing is tied to Filament’s merger with Jupiter Acquisition Corp. (NASDAQ: JAQC), a special purpose acquisition company(SPAC), which received regulatory approval in mid-November. Upon closing of the SPAC merger, the combined entity will be rebranded as TopCo. According to Filament, they aim to use the new financing to propel themself towards a listing on the Nasdaq, marking a significant milestone in its business strategy.
In addition to the financing from Helena, Filament announced that they had also completed a separate fundraising round, raising C$900,000 through the issuance of unsecured convertible notes to certain investors affiliated with Jupiter and Filament. The company said it plans to raise an additional $900,000 through this method.
Filament CEO Ben Lightburn expressed confidence in the financings, emphasizing their role in de-risking milestones and supporting the execution of the proposed business combination. Despite reporting a C$1.3 million net loss in the most recent quarter, Filament sees the financing as crucial for advancing internal operational and drug development initiatives.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector

• Canopy Growth successfully concluded BioSteel sale.
• Jushi filed CA$600 million shelf prospectus for strategic flexibility.
• MTL Cannabis reported soaring Q2 revenue after merger.
• 22nd Century Group is streamlining operations by selling its hemp division for $2.25 million.
Key Takeaways; Psychedelic Sector
• Awakn’s recent regulatory and ethical approval for a Phase III clinical trial was highlighted.
• Numinus Wellness reported revenue surge for fiscal year 2023, despite margin challenges.

As we enter the last month of 2023, the cannabis sector remains in the spotlight, showcasing notable developments and market dynamics. In the aftermath of a turbulent October, cannabis stocks made significant strides in November, with the Cannabis Stock Index rebounding from a substantial loss. However, despite a promising start to December, the index still grapples with a 17.5% decline for the year. This year’s narrative has been dominated by the anticipation of potential rescheduling within the cannabis industry. The shift, which is expected to move cannabis from Schedule 1 to Schedule 3, carries significant implications for the industry. However, the timeline and certainty of this adjustment remain elusive.
Below is a weekly roundup on the cannabis and psychedelic sectors.

Top Marijuana Companies for Week

#1: Canopy Growth

Canopy Growth Corporation (CGC: NASDAQ) announced the successful completion of two significant sale transactions involving BioSteel Sports Nutrition Inc. and BioSteel Manufacturing, LLC. The proceedings were carried out under the Companies’ Creditors Arrangement Act (CCAA), resulting in combined gross proceeds of $30.4 million.
The first transaction involved the sale of BioSteel Canada’s assets to the Coachwood Group, as outlined in the asset purchase agreement dated November 9, 2023. Simultaneously, another sale transferred the assets of BioSteel Manufacturing to a third party, in line with a separate asset purchase agreement dated the same day.
The completion of these deals marked a crucial step in Canopy Growth’s restructuring strategy, as the company aims to streamline its operations, focusing more on its core cannabis business and adopting an asset-light operating model. The company stated that they plan to utilize a portion of the proceeds to repay debt, leading to a further reduction in interest expenses.
Judy Hong, Canopy Growth’s Chief Financial Officer, highlighted the significance of these transactions, emphasizing their role in improving the company’s balance sheet. “With the completion of these two sale transactions, we have completed another critical action to focus Canopy Growth’s business on our core cannabis operations and can now realize the proceeds of sale to further improve the Company’s balance sheet,” said Hong.

#2: Jushi Holdings
Jushi Holdings Inc. (OTC: JUSHF), a Florida-based cannabis multistate operator, submitted a preliminary short-form base shelf prospectus in Canada with the goal of raising up to $CA600 million (approximately $442 million). This filing allows Jushi to issue a variety of securities over a 25-month period, including subordinate voting shares, preferred shares, subscription receipts, debt securities, convertible securities, warrants, and units.

The primary purpose of this filing, as stated in the news release, is to maintain financial flexibility. Jushi said that they aim to be well-positioned to respond to significant regulatory improvements and pursue opportunistic acquisitions within the cannabis industry. The filing was made with the securities commissions for each of Canada’s provinces and territories. The terms of any future offerings of securities using this shelf prospectus will be outlined in a prospectus supplement, providing further details and specifications.
This move follows Jushi’s closure of a private offering almost a year ago, which successfully generated proceeds totaling $72 million. The latest filing reflects the company’s strategic approach to secure financial flexibility and capitalize on emerging opportunities in the evolving cannabis market.

#3: MTL Cannabis

MTL Cannabis Corp. (CSE: MTLC) announced impressive financial results for the quarter and half-year ending September 30, following a reverse takeover with Canada House Cannabis Group Inc. in July. Formerly known as Montréal Cannabis Médical Inc., the newly merged Canadian company reported a remarkable 366% increase in revenue, reaching C$23.15 million, compared to C$4.96 million in the same quarter the previous year.
Net revenue also experienced a substantial surge, reaching C$19 million for the quarter, up from C$3.89 million in the corresponding quarter of 2022. Additionally, the company reported a gross profit of C$6.3 million, a significant improvement from C$1.25 million in the same quarter last year.
Positive trends were also observed in operating income, which turned positive at C$843,359, a notable improvement from a loss of C$91,811 in the same period last year. Net income followed suit, with the company reporting C$1.99 million, a reversal from a loss of C$604,314 in the previous year’s quarter.
The positive financial changes were also evident in the company’s cash flow statements. Net cash inflows from operating activities amounted to C$7.3 million, compared to a net outflow of C$1.97 million in the same period last year. However, the company used C$162,255 in investing activities and C$4.64 million in financing activities during the quarter.
MTL Cannabis CEO, Michael Perron, attributed the success to the company’s focus on quality and dedication to providing excellent products and services to recreational customers and medical patients. He stated, “Our focus on quality and dedication to providing the best products and services to our recreational customers and medical patients has been the foundation for our business, and we are seeing that focus being reflected in our financial results.”
#4: 22nd Century Group
Biotech company 22nd Century Group, Inc. (NASDAQ: XXII) initiated the sale of its hemp operations, valued at $2.25 million, in a strategic move to streamline operations and reduce costs. The majority of its GVB Biopharma division is set to be acquired by Specialty Acquisition Corp., a Nevada-based entity with affiliations to current GVB employees. The deal comprises $1 million in cash and a further 12%, $1.25 million promissory note.
The decision to sell is aimed at deleveraging 22nd Century’s balance sheet, and the company stated that they plan to utilize the proceeds from the sale for this purpose. The Buffalo, New York-based company will also retain the right to recover an outstanding insurance payout related to a 2022 fire at a GVB manufacturing facility in Grass Valley, Oregon, currently valued at around $9 million.
The transaction is expected to conclude in December, subject to meeting closing conditions, including financing from the buyer and approval from 22nd Century’s senior lender.
Top Psychedelic Companies for Week

#1: Awakn

Awakn Life Sciences Corp. (OTC: AWKNF), recent regulatory and ethical approval for a Phase III clinical trial was highlighted by Benzinga, a leading newsfeed. Recently, Awakn received regulatory and ethical approval for a Phase III clinical trial of AWKN-P001, its lead program designed for the treatment of Severe Alcohol Use Disorder (SAUD). The approval was granted by the U.K. Medicines and Healthcare Regulatory Agency (MHRA) and the Health Research Authority in the UK. The Phase III trial will commence in Q1 2024 with the enrollment of 280 patients.
AWKN-P001 is a groundbreaking treatment that combines the NMDA receptor-modulating drug ketamine with psycho-social support, targeting the most severe form of alcohol use disorder. In prior Phase II studies, the treatment demonstrated promising results, achieving an 86% abstinence rate six months post-treatment, compared to 2% pre-trial and 25% in the current standard of care.
The trial, funded by Awakn, the University of Exeter, and a partnership between the National Institute for Health and Care Research (NIHR) and the Medical Research Council (MRC), marks a pivotal step in Awakn’s commercial journey. The company’s CEO, Anthony Tennyson, emphasized that the regulatory and ethical approval reflects Awakn’s commitment to scientific rigor and patient well-being; “Our Phase 3 clinical trial represents a crucial bridge between cutting-edge science and a commercially viable solution for addressing severe alcohol use disorder,” Tennyson said in a press statement.

#2: Numinus Wellness

Numinus Wellness Inc. (OTC: NUMIF) announced a significant surge in revenue for its fiscal year ending August 31, 2023. The company reported a 256.9% increase in revenue, attributing the growth to expanded services in North America, increased clinic appointments, and a practitioner-friendly licensing model.
In the fourth quarter of 2023, Numinus recorded a revenue of $6.1 million, marking a 1.7% increase from the previous quarter and a substantial 46.8% increase from the same quarter the previous year.
However, the positive trends were accompanied by a decline in gross margin to 29.5% in the fourth quarter of 2023, down from 34.5% in the previous quarter. Numinus attributed this decrease to increased investment in full-time practitioners and varying clinic performances. In response, the company implemented cost-saving measures, including the closure of an underperforming clinic, resulting in reduced operating expenditures of $7.9 million in the fourth quarter, down from $9.2 million in the previous quarter.
Despite the challenges, Numinus successfully lowered its monthly cash burn to under $1 million as of October. The company reported a total cash balance of $8.6 million and working capital of $7.4 million. Numinus expressed optimism about the anticipated approval of MDMA-assisted therapy by the FDA, which, if approved, would open additional opportunities for the company to deploy its unique service model using this alternative treatment modality.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector
• Organigram received C$124.6 million investment from BAT; the company also announced the appointment of an interim CFO.
• Trulieve posts robust Q3 2023 financial results, showcasing strong financial performance, debt reduction, and strategic growth initiatives.
• Canopy Growth reported narrowed Q2 losses, indicating a positive shift amid restructuring efforts.
• Curaleaf’s Q3 results showcased strategic shifts amid expansion and exits.
• TerrAscend achieved record third quarter 2023 results and raised full-year guidance.
• Ascend Wellness impressed in Q3 surpassing revenue estimates by 33%.
Key Takeaways; Psychedelic Sector
• Cybin plummeted 15% following $64 million offering announcement.
• Awakn’s Prof. David Nutt is the world’s top psychopharmacologist according to ScholarGPS.

This week marked another earnings week as majority of multistate operators in the cannabis sector reported their financial results. Below is a weekly overview of the cannabis and psychedelic sectors, summarizing the noteworthy news that impacted the industry during the initial week of November.
Top Marijuana Companies for Week

#1: Organigram
Organigram Holdings Inc. (NASDAQ: OGI) witnessed a remarkable surge of over 35% on Monday following the announcement of a significant C$124.6 million investment from BT DE Investments Inc., a subsidiary of British American Tobacco p.l.c.(LSE: BATS) (NYSE: BTI). British American Tobacco (BAT), a leading consumer goods business, aims to strengthen its strategic partnership with Organigram through this investment.
Organigram stated that the investment will be used to create a strategic investment pool named “Jupiter,” aiming to accelerate Organigram’s growth plans beyond Canada. This includes geographic expansion, technological advancements, and product development. The strategic move will undoubtedly position Organigram as a prominent player in the rapidly consolidating cannabis market.
This strategic partnership between Organigram and BAT was established in March 2021, and has yielded significant progress, particularly through the Product Development Collaboration (PDC) agreement. The PDC is focused on developing innovative cannabis science and research and development (R&D) projects. The collaboration is in the late stages of developing various products, including emulsions, novel vapor formulations, flavor innovations, and packaging solutions, expected to be applied to Organigram’s portfolio in 2024.
In other news, Organigram announced the appointment of Paolo De Luca as interim Chief Financial Officer, effective November 13, 2023. The company said that the current CFO, Derrick West, was transitioning away from the role to focus on health and recovery after surgery. De Luca, the current Chief Strategy Officer, previously served as Organigram’s CFO between 2017 and 2020.

#2: Trulieve
Trulieve Cannabis Corp. (OTC: TCNNF) reported its financial results for the third quarter of 2023, showcasing substantial cash generation and strategic financial moves. The company revealed cash flow from operations of $93 million and free cash flow of $87 million during the quarter. Notable achievements included a reduction in debt through the purchase of $57 million of 2026 notes, resulting in a 16.5% discount to par, and the announcement of the redemption of $130 million of 2024 notes, projecting $20 million in interest savings.
Moreover, Trulieve reported a revenue of $275 million, with 96% generated from retail sales, and achieved a GAAP gross margin of 52%. Additionally, the company opened new dispensaries, expanded its reach outside Florida, and realized a 235% increase in Maryland traffic in Q3 compared to Q2.
The financial highlights also included an anticipated operating cash flow of at least $100 million and free cash flow of at least $70 million for the year 2023. Trulieve also emphasized its focus on strengthening its balance sheet and commitment to non-dilutive measures. Other significant developments that were highlighted included, the redemption of senior secured notes and the filing of amended federal tax returns for a $143 million refund.
The company’s CEO, Kim Rivers, expressed confidence in the company’s strong cash generation, strategic positioning, and readiness for future growth catalysts; “This year our team has done a phenomenal job executing on our plan to generate cash while making investments to support future growth,” said Kim Rivers.

#3: Canopy Growth
Canadian cannabis producer Canopy Growth Corporation (NASDAQ: CGC) showcased improved financials for the second quarter ended September 30, 2023, indicating signs of a potential turnaround. The company reported a net revenue of CAD 70 million, accompanied by a gross margin of 34%, a notable improvement from the negative margin reported in the same period the previous year. Additionally, operating expenses were down nearly 80% at C$30.43 million, and the company reduced costs by C$54 million during the quarter. This positive shift can be attributed to cost-cutting measures and restructuring initiatives that the company has been undertaking.
Canopy Growth’s net revenue, however, fell 21% to C$69.6 million. This indicates that the company is still experiencing liquidity issues, with CFO Judy Hong stating that significant actions have been taken to eliminate near-term debt obligations.
In terms of product development, Canopy Growth expanded its portfolio, resulting in increased market share. The medical cannabis segment reported its fourth consecutive quarter of revenue growth. Internationally, the company stated that they are still focusing on high-growth markets such as Australia and working to obtain EU-GMP certification for its facility in Kincardine, Ontario, to meet global medical cannabis demand.
Despite positive improvements in its U.S. operations and plans for market expansion, Canopy Growth is still facing regulatory hurdles regarding the creation of a new entity that would incorporate both its Canadian and U.S. investments. The company said that they are actively negotiating and engaging in discussions with the U.S. Securities and Exchange Commission to address concerns and explore additional structural amendments for the financial deconsolidation of Canopy USA from Canopy Growth’s results.

#4: Curaleaf
Curaleaf Holdings Inc. (OTC: CURLF) announced its third-quarter financial results on Friday, showcasing a 2% increase in net revenue to $333.2 million compared to the same period in 2022. While this growth was attributed to the company’s expansion and diversification efforts, it fell slightly short of analysts’ expectations by approximately $7 million.
The company reported a net loss of $92.3 million for the quarter, a significant rise from the $51.4 million loss in Q3 2022. This increase in losses was primarily influenced by a non-cash impairment charge related to the company’s exit from operations in Michigan and Kentucky.
Despite the overall net loss, Curaleaf’s retail sector experienced a 6% revenue increase, reaching $273.2 million. This growth was fueled by the launch of adult-use sales in Maryland and Connecticut, as well as ongoing expansion efforts in New Jersey.
Wholesale revenue, however, remained unchanged from the second quarter and showed a 12% decline from the previous year. The company attributed this decrease to strategic inventory reductions.
In addition, the company’s balance sheet reflects an aggressive investment strategy, with $49.4 million in capital expenditure focused on cultivation and retail expansion in key markets. As of the end of the quarter, Curaleaf had $118.1 million in cash and a net debt of $584.6 million.
Geographically, Curaleaf has shifted its focus, with exits from Michigan and Kentucky and agreements to sell its Oregon assets. The company has also made strides in the European market, acquiring assets in Portugal and initiating sales in the U.K. and Poland.

#5: TerrAscend
TerrAscend Corp. (OTC: TSNDF), a prominent North American cannabis operator, reported remarkable financial results for the third quarter ending September 30, 2023. The company’s net revenue surged to $89.2 million, marking a 34.7% increase year-over-year and a 23.7% sequential growth. Notably, TerrAscend achieved a gross profit margin of 53.6%, showcasing a 340-basis point improvement from the previous quarter.
The company’s adjusted EBITDA from continuing operations reached $24.2 million, demonstrating an 89% sequential increase and a 27.1% adjusted EBITDA margin. Encouraged by these positive trends, TerrAscend revised its full-year 2023 guidance, anticipating net revenue and adjusted EBITDA from continuing operations to reach $320 million and $73 million, respectively. This adjustment signifies a robust 29% and 87% year-over-year growth, underscoring the company’s sustained momentum.
TerrAscend’s impressive financial performance is attributed to several strategic moves, including the successful transition to adult-use sales in Maryland, strengthened market share in New Jersey, improved gross margins in Michigan, and renewed growth in both retail and wholesale sectors in Pennsylvania. The company’s expansion strategy, from ‘deep, not wide,’ is evolving to ‘deep and wide,’ reflecting its confidence in capitalizing on emerging opportunities while maintaining control over its terms.
In addition to financial achievements, TerrAscend celebrated operational milestones during the third quarter, marking its eighth consecutive quarter of sequential net revenue growth and the fifth consecutive quarter of positive cash flow from continuing operations. The company also secured the second position in the New Jersey market, boasting an 18.6% market share.

#6: Ascend Wellness
New York-based Ascend Wellness Holdings, Inc. (OTC: AAWH) reported a robust third-quarter performance, exceeding analysts’ revenue estimates by an impressive 33%. The company’s strategic initiatives, which include cost-cutting measures and operational optimization, played a crucial role in achieving these strong results.
Ascend’s gross revenue for the period ending September 30 rose by 26.6% from the previous year, reaching $169.9 million. Net revenue, excluding internal sales impact, demonstrated an even more substantial growth of 27%, successfully mitigating broader retail challenges. Additionally, the company’s emphasis on same-store sales proved fruitful, with retail revenue increasing by 22.3% to $101.3 million, particularly driven by strong consumer demand, especially in Maryland where adult-use sales commenced earlier this year.
Ascend’s wholesale operations also flourished, experiencing a notable 33.4% rise in gross revenue year-over-year, reflecting a well-received wholesale strategy in a market evolving in sophistication and scale.
Despite reporting a net loss of $11.2 million, there was a marked improvement compared to the previous year. The adjusted EBITDA improved by 38.5% from the previous quarter, with sequential margin growth of 356 basis points. Moreover, Ascend’s financial position, with $63.9 million in cash and cash equivalents, provides a cushion, although the company maintains a net debt position of $243.5 million. The operational cash flow was also encouraging, with Ascend generating $24.2 million in the quarter, marking its third consecutive period of operational cash positivity.
Newly appointed CEO John Hartmann expressed optimism, stating, “In my first full quarter as Ascend’s CEO, we’ve been diligently optimizing operations and fortifying our team. Early signs of results are encouraging.”

Top Psychedelic Companies for Week

#1: Cybin
Cybin Inc. (NYSE: CYBN) announced a firm commitment underwritten offering of 66,666,667 units at a price of US$0.45 per unit. This move aimed to generate approximately US$30 million in gross proceeds, with an additional US$34 million possible upon full exercise of the warrants. The units comprised common shares and purchase warrants, with A.G.P./Alliance Global Partners serving as the sole book-running manager for the offering. The closing was expected around November 15, 2023, pending market and customary conditions, including approval from the Neo Exchange Inc.
The net proceeds, designated for advancing the CYB003 and deuterated DMT programs and general corporate purposes, were part of a prospectus supplement filed with the Ontario Securities Commission and the United States Securities and Exchange Commission (SEC). Prospective investors were advised to review the Base Shelf Prospectus and related documents before making investment decisions.
Simultaneously, Cybin suspended sales under the Lincoln Park Capital Fund agreement, which allowed the company to issue common shares to LPC. The decision to halt purchases under this agreement aligned with the company’s strategic focus on the ongoing public offering.
This announcement triggered a notable 15% drop in Cybin’s stock value on the same day, reflecting the market’s response to the significant financial decision.

#2: Awakn
In a groundbreaking achievement, Prof. David Nutt, a renowned figure in the field of psychopharmacology, was ranked as the world’s leading psychopharmacologist by ScholarGPS. This prestigious acknowledgment is not only a testament to Professor Nutt’s remarkable career but also a reflection of his current role as a vital part of Awakn Life Sciences Corp. (OTC: AWKNF), a company committed to developing innovative treatment options for individuals struggling with addiction.
The recognition of Prof. Nutt as the world’s top psychopharmacologist is not just an accolade; it is a reflection of his profound dedication to improving the lives of those affected by addiction. As the leader of Awakn’s distinguished team, Prof. David Nutt plays a pivotal role in developing groundbreaking treatments for addiction. This milestone serves as a testament to the dedication and commitment of Awakn Life Sciences in their mission to address addiction-related challenges with innovative, science-based solutions.
The partnership between Awakn Life Sciences and Prof. David Nutt stands as a beacon of hope for those who have struggled with addiction, as well as a testament to the power of science and innovation in addressing one of society’s most pressing health crises. This collaboration marks a significant step forward in the ongoing battle against addiction.

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Weekly Roundup on the Cannabis Sector & Psychedelic Sector

Key Takeaways; Cannabis Sector
• Aurora resolved a patent dispute with Willow Biosciences; they also announced Q2 conference call.
• Canadian cannabis giant Tilray has taken a green leap with hemp packaging to reduce plastic waste.
• 22nd Century Group slashed debt by $8.1 million in a strategic move.
Key Takeaways; Psychedelic Sector
• COMPASS Pathways announced a CFO transition.
• Cybin secured additional patents for its DMT program, expanding its psychedelic portfolio.
• Awakn’s Prof. David Nutt is the world’s top psychopharmacologist according to ScholarGPS.
Below is a weekly roundup on the cannabis and psychedelic sectors. In this ever-evolving landscape, we explore the major developments and groundbreaking initiatives happening among companies operating in these industries; from advancements in medical research, therapeutic applications to shifts in legal frameworks and current market trends.
Top Marijuana Companies for Week
#1: Aurora Cannabis
Aurora Cannabis Inc. (NASDAQ: ACB), recently announced the settlement of a patent dispute with Willow Biosciences Inc. (OTC: CANSF). The dispute, which began in July 2021, centered around allegations that Willow’s biosynthetic process for synthesizing cannabinoids had infringed on patents co-owned by Aurora, the University of Saskatchewan, and Canada’s National Research Council.
The patented technology in question was developed by Jonathan Page, the co-founder of Anandia Labs and former chief science officer at Aurora, along with his colleagues. Their work at the University of Saskatchewan and the NRC involved identifying key enzymes and corresponding genes in the biosynthetic pathways of cannabis plants.
Aurora acquired Anandia in 2018 and initiated the patent infringement action against Willow. While the settlement terms remain confidential, Aurora’s CEO, Miguel Martin, expressed satisfaction with the resolution, emphasizing the importance of protecting and enforcing their intellectual property rights. He also underscored Aurora’s pioneering role in genetics work within the Canadian cannabis industry.
Additionally, in other news related to Aurora Cannabis, the company announced that it has scheduled a conference call to discuss its financial results for the second quarter of fiscal year 2024 on November 9, 2023. The call will be hosted by Aurora’s Chief Executive Officer, Miguel Martin, and Chief Financial Officer, Glen Ibbott. The financial results are set to be reported after the close of markets on the same day.
#2: Tilray
Tilray Brands, Inc. (NASDAQ: TLRY), a prominent Canadian cannabis producer, initiated a significant effort to reduce the use of single-use plastics in its packaging and product components. This transition includes converting packaging, pre-rolls, and vape components to hemp-based materials. This move is considered the first major commitment by a large Canadian cannabis producer to address the issue of plastic waste in the industry and could potentially set a precedent for others to follow.
Tilray estimates that its new hemp-based packaging program will divert approximately 131,000 kilograms (288,805 pounds) of plastic waste from landfills each year. The environmental impact of cannabis legalization in Canada has drawn attention, with packaging waste being a prominent concern.
A report by a government-appointed panel highlighted the challenges of recycling plastic cannabis packaging, particularly vaping cartridges and batteries, due to the presence of metal, glass, electronics, and batteries. It was also pointed that Canadian cannabis companies have been producing more products than they can sell, resulting in excess inventory.
Tilray stated that its transition to hemp-based packaging will commence with its Good Supply brand and later expand to include other brands like Riff and Broken Coast. According to the company, the Good Supply hemp initiative will include eco-friendly “hemp tubes” for pre-rolls and Pax Pods cartridges and hemp-composite mouthpieces for 510 vape cartridges. Furthermore, Tilray will replace plastic bags for whole-flower products with bags made from recycled content, diverting an estimated 38,000 kilograms of plastic waste from landfills annually.
The company believes that this initiative is beneficial for both business and the environment, citing research that shows consumers are 50% more likely to purchase cannabis products in sustainable packaging. The move could potentially influence competitors in the cannabis industry to adopt similar eco-friendly practices. Tilray originally pledged to adopt hemp-based packaging during a conference call with stock analysts in January 2023, with the goal of diverting thousands of kilograms of plastic waste from landfills.
#3: 22nd Century Group
Hemp biotech company 22nd Century Group, Inc. (NASDAQ: XXII), specializing in hemp, tobacco, and hops, successfully decreased its senior secured debt by $8.1 million. This achievement followed an amendment and waiver process with its lenders, reducing the outstanding debt from $22.1 million to approximately $14 million.
This significant reduction stems from a waiver and repayment of the required $7.5 million minimum cash balance specified in the original debenture agreements. Furthermore, an existing promissory note was reassigned as part of the deal, with $600,000 of the note allocated to reduce the outstanding principal and $2 million directed towards lowering the put price associated with the lenders’ outstanding warrants, a portion of which was subsequently canceled.
The remaining principal loan balance of $14 million and the outstanding $500,000 of the put price are now due at maturity in 2026, following the original terms of the debenture agreements. Chief Financial Officer, Hugh Kinsman, noted that this principal reduction will save 22nd Century Group approximately $500,000 in cash annually, emphasizing the company’s commitment to actively manage their balance sheet and focus on cost reduction initiatives.
Top Psychedelic Companies for Week
#1: Compass Pathways
COMPASS Pathways plc (NASDAQ: CMPS) recently announced the departure of its Chief Financial Officer, Mike Falvey, who is set to leave the company on November 3, 2023, to explore new opportunities. The company stated that Mary-Rose Hughes, who is currently serving as the Vice President of Finance, will take on the role of interim CFO with immediate effect, while the company initiates a search for a permanent replacement.
Compass Pathways expressed its gratitude to Mike Falvey for his leadership and substantial contributions during his tenure, highlighting his pivotal role in their recent successful private placement. According to Compass, this financing round not only extended the company’s cash runway, ensuring financial stability beyond expected phase 3 clinical data milestones, but also attracted significant investments from leading biotech investors.
The company stated that Mary-Rose Hughes, who joined Compass in May 2020 as its second finance team member, is well-versed in the company’s operations and has been instrumental in overseeing various financial aspects, including treasury, tax, financial planning and analysis, and external reporting. She also played a crucial role in Compass’s initial public offering (IPO), follow-on public equity offering, term loan facility, and private placement financing.
Furthermore, Compass Pathways informed investors that they will release their financial results for the third quarter of 2023 and provide updates on recent business developments on November 2, ensuring transparency and ongoing communication with their stakeholders.
#2: Cybin
Cybin Inc. (NYSE: CYBN) received two patent grants from the United States Patent and Trademark Office, bolstering its deuterated N, N-dimethyltryptamine (DMT) program. Following its recent acquisition of Small Pharma Inc., Cybin now boasts 32 granted patents and over 170 pending applications, establishing a commanding position in the development of innovative tryptamine-based therapeutics.
The two newly granted patents offer protection for Cybin’s deuterated DMT program, covering composition of matter, medical use, and the synthesis of certain DMT analogs. These patents are essential in safeguarding Cybin’s proprietary deuterated DMT compounds, CYB004 and SPL028, both of which are currently in Phase I clinical trials. These compounds aim to provide an extended DMT psychedelic experience with a short-duration drug profile, allowing for optimized dose formulations and distinct therapeutic benefits. Preliminary findings indicate that both CYB004 and SPL028 are well-tolerated and elicit a psychedelic experience lasting under an hour.
#3: Awakn
In a groundbreaking achievement, Prof. David Nutt, a renowned figure in the field of psychopharmacology, was ranked as the world’s leading psychopharmacologist by ScholarGPS. This prestigious acknowledgment is not only a testament to Professor Nutt’s remarkable career but also a reflection of his current role as a vital part of Awakn Life Sciences Corp. (OTC: AWKNF), a company committed to developing innovative treatment options for individuals struggling with addiction.
The recognition of Prof. Nutt as the world’s top psychopharmacologist is not just an accolade; it is a reflection of his profound dedication to improving the lives of those affected by addiction. As the leader of Awakn’s distinguished team, Prof. David Nutt plays a pivotal role in developing groundbreaking treatments for addiction. This milestone serves as a testament to the dedication and commitment of Awakn Life Sciences in their mission to address addiction-related challenges with innovative, science-based solutions.
The partnership between Awakn Life Sciences and Prof. David Nutt stands as a beacon of hope for those who have struggled with addiction, as well as a testament to the power of science and innovation in addressing one of society’s most pressing health crises. This collaboration marks a significant step forward in the ongoing battle against addiction.

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