Provectus Biopharmaceuticals, Inc. (NYSEMKT:PVCT), a clinical-stage oncology and dermatology biopharmaceutical company (“Provectus” or the “Company”), today confirmed that the Company received a notice dated October 13, 2016 from the staff of NYSE Regulation, Inc. (“NYSE Regulation”) indicating that it has determined to suspend trading of the Company’s common stock trading under the symbol “PVCT” and its class of warrants trading under the symbol “PVCTWS” immediately and to commence proceedings to delist the Company’s common stock and warrants from NYSE MKT LLC (“NYSE MKT”). NYSE Regulation notified the Company that it is no longer suitable for listing pursuant to Section 1003(f)(v) of the NYSE MKT Company Guide, due to the “abnormally low” trading price of its common stock.

Provectus has a right to a review of this determination by a NYSE MKT Listing Qualifications Panel. The NYSE MKT will apply to the Securities and Exchange Commission (“SEC”) to delist the Company’s common stock and warrants upon completion of all applicable procedures, including any appeal by Provectus of the NYSE Regulation staff’s decision.

Provectus plans to appeal the decision of the NYSE MKT. The Company’s common stock began trading on the OTC Pink under the trading symbol PVCT, and its previously listed warrants began trading on the OTC Pink under the trading symbol PVCTWS on Friday, October 14, 2016. The Company anticipates that its common stock and its previously listed warrants will trade on the OTCQB under the same trading symbols beginning on Monday, October 17, 2016.

In an effort to regain compliance with the listing standards of the NYSE MKT, the Company filed a preliminary proxy statement with the SEC on October 5, 2016 to request that its stockholders approve, at a special meeting of stockholders to be held on Monday, November 14, 2016, at 1:00 p.m. Eastern Time at 265 Brookview Centre Way, Suite 600, Knoxville, Tennessee 37919, among other items, a reverse stock split, which will be at the discretion of the Company’s board of directors to effectuate if the proposal receives the requisite stockholder approval at the special meeting. The reverse stock split, if approved by stockholders and effectuated by the Company’s board of directors, will combine each 10 to 50 shares of common stock (with the exact ratio to be determined in the sole discretion of the Company’s board of directors) into one new share of common stock, and will increase the price of the Company’s common stock accordingly. A reverse stock split will be necessary for the Company to maintain its listing on the NYSE MKT, unless the Company’s stock price begins trading at higher levels for a sustainable period of time.

There can be no assurance, however, that the Company’s stockholders will approve the reverse stock split. Even if stockholders approve the reverse stock split and the Company effectuates the reverse stock split, the Company may still be subject to delisting if the price of its common stock again falls below $0.06 or fails to rise above $0.20 and the Company is not otherwise able to meet applicable listing requirements of the NYSE MKT.

Peter R. Culpepper, Interim CEO and COO of Provectus, stated, “we are committed to persevere in our efforts for both patients and stockholders to win, and we intend to be active in our communication with stockholders up to and including our quarterly investor conference call in November, which is planned to coincide with the filing of our Quarterly Report on Form 10-Q for the quarter ended September 30, 2016 with the SEC.”