Proteostasis Therapeutics, Inc. (NASDAQ:PTI) Files An 8-K Regulation FD Disclosure

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Proteostasis Therapeutics, Inc. (NASDAQ:PTI) Files An 8-K Regulation FD Disclosure

Item7.01

Regulation FD Disclosure.

Spokespersons of the Company plan to present the information in
the presentation slides attached hereto as Exhibit 99.1 at a
session or sessions on June 8-9, 2017 being held at the 40th
European Cystic Fibrosis Society conference in Seville, Spain.

The furnishing of the attached presentation is not an admission
as to the materiality of any information therein. The information
contained in the slides is summary information that is intended
to be considered in the context of more complete information
included in the Companys filings with the U.S. Securities and
Exchange Commission, or the SEC, and other public announcements
that the Company has made and may make from time to time by press
release or otherwise. The Company undertakes no duty or
obligation to update or revise the information contained in this
report, although it may do so from time to time as its management
believes is appropriate. Any such updating may be made through
the filing of other reports or documents with the SEC, through
press releases or through other public disclosures.

The information in this Item7.01 of this Current Report on Form
8-K and Exhibit 99.1 attached hereto shall not be deemed filed
for purposes of Section18 of the Securities Exchange Act of 1934,
as amended, or otherwise subject to the liabilities of that
section or Sections 11 and 12(a)(2) of the Securities Act of
1933, as amended. The information contained in this Item7.01 and
in the presentation attached as Exhibit 99.1 to this Current
Report shall not be incorporated by reference into any filing
with the SEC made by the Company, whether made before or after
the date hereof, regardless of any general incorporation language
in such filing, except as expressly set forth by specific
reference in such filing.

Item9.01 Financial Statements and Exhibits.

(d) Exhibits.

Exhibit

No.

Description

99.1 Presentation slides, furnished herewith.


About Proteostasis Therapeutics, Inc. (NASDAQ:PTI)

Proteostasis Therapeutics, Inc. is a biopharmaceutical company. The Company is engaged in discovery and development of therapeutics that treat diseases caused by an imbalance in the proteostasis network, a set of pathways that control protein biosynthesis, folding, trafficking and clearance. It has developed the Disease Relevant Translation (DRT) technology platform, a drug screening approach for identifying highly translatable therapeutics based on predictive and functionally pertinent phenotypic assays and disease relevant models. Using this platform, it has identified a new class of small molecules, amplifiers that modulate proteins in the proteostasis network. It is developing and intend to commercialize its lead amplifier of CFTR protein, PTI-428, to improve CFTR protein function. It also focuses on developing PTI-NC-733, PTI-130, Usp14 program and unfolded protein response (UPR) program. PTI-130 is a small molecule amplifier.