Blueprint Medicines Corporation (NASDAQ:BPMC) Files An 8-K Entry into a Material Definitive Agreement

ME Staff 8-k
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Blueprint Medicines Corporation (NASDAQ:BPMC) Files An 8-K Entry into a Material Definitive Agreement

Blueprint Medicines Corporation (NASDAQ:BPMC) Files An 8-K Entry into a Material Definitive Agreement
Item 1.01  Entry into a Material Definitive Agreement.

On June 28, 2019, Blueprint Medicines Corporation (the “Company”) entered into a fifth amendment to its collaboration and license agreement, as amended, with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.  (collectively, “Roche”), to which the Company and Roche agreed to modify certain time periods related to the screening activities under the collaboration and modify certain criteria related to leftover targets under the collaboration.

The foregoing description of the material terms of the fifth amendment to the collaboration and license agreement with Roche is qualified in its entirety by reference to the complete text of such amendment, a copy of which is attached as Exhibit 10.1 to this Current Report on Form 8-K.

Item 9.01    Financial Statements and Exhibits.

(d) Exhibits.

2

Blueprint Medicines Corp Exhibit
EX-10.1 2 ex-10d1.htm EX-10.1 bpmc_Ex10_1 Exhibit 10.1   [***] Certain information in this document has been omitted from this exhibit because it is both (i) not material and (ii) would be competitively harmful if publicly disclosed.   FIFTH AMENDMENT TO COLLABORATION AND LICENSE AGREEMENT This  Fifth Amendment (this “Amendment”),…
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About Blueprint Medicines Corporation (NASDAQ:BPMC)

Blueprint Medicines Corporation is a biopharmaceutical company. The Company focuses on patients with genomically defined diseases driven by abnormal kinase activation. The Company focuses on crafting drug candidates with therapeutic windows that provide clinical responses to patients without adequate treatment options. The Company has developed a small molecule drug pipeline in cancer and a genetic disease. The Company’s drug candidate, BLU-285, targets KIT Exon 17 mutants and PDGFRa D842V, which are abnormally active receptor tyrosine kinase mutants that are drivers of cancer and proliferative disorders. It is engaged in developing BLU-285 for patients with systemic mastocytosis (SM), a myeloproliferative disorder of the mast cells, and defined subsets of patients with gastrointestinal stromal tumor (GIST). Its drug candidate, BLU-554, targets FGFR4, a kinase that is aberrantly activated and is a driver of disease in a defined subset of patients with hepatocellular carcinoma (HCC).