TREVENA, INC. (NASDAQ:TRVN) Files An 8-K Entry into a Material Definitive Agreement
Item 1.01
On December 4, 2019, Trevena, Inc. (the “Company”) and Pfizer CenterOne Group of Pfizer Inc. (“Pfizer”) entered into an amendment (dated December 2, 2019) (the “Amendment”) to the Development and Supply Agreement, dated as of December 15, 2016 (the “Agreement”). to the Amendment, the Company and Pfizer agreed to, among other things, (i) clarify that the first “commercial year” shall commence after the month in which the Company makes its first bona fide commercial sale of a product manufactured by Pfizer in accordance with the Agreement, and (ii) modify the termination rights, such that either party may terminate the Agreement if the U.S. Food and Drug Administration or other regulatory authority does not grant regulatory approval for a product covered by the Agreement by December 31, 2021.
Except as modified by the Amendment, all terms and conditions of the Agreement remain in full force and effect.
The foregoing summary of the Amendment is not complete and is qualified in its entirety by reference to the Amendment, a copy of which is filed as Exhibit 10.1 to this Current Report on Form 8-K and incorporated herein by reference.
(d) Exhibits.
| Exhibit No. | Description | |
| 10.1^ | Amendment No. 2 to Development and Supply Agreement, by and between the Company and Pfizer CenterOne Group of Pfizer Inc, dated as of December 2, 2019. |
^ to Item 601(b)(10)(iv) of Regulation S-K promulgated by the Securities and Exchange Commission (the “SEC”), certain portions of this exhibit have been redacted. The Company hereby agrees to furnish supplementally to the SEC, upon its request, an unredacted copy of this exhibit.
TREVENA INC Exhibit
EX-10.1 2 tm1924641d1_ex10-1.htm EXHIBIT 10.1 Exhibit 10.1 AMENDMENT NO. 2 TO DEVELOPMENT AND SUPPLY AGREEMENT This Second Amendment (“2nd Amendment”) is made as of this 2nd day of December 2019 (the “Amendment Effective Date”) is between Trevena,…
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About TREVENA, INC. (NASDAQ:TRVN)
Trevena Inc. is a clinical-stage biopharmaceutical company. The Company discovers, develops and intends to commercialize therapeutics that use an approach to target G protein coupled receptors (GPCRs). Using its product platform, the Company has identified and advanced three differentiated product candidates: Oliceridine (TRV130), TRV027 and TRV250. Its TRV130 is a Mu-receptor G protein Pathway Selective (Mu-GPS) modulator that activates G protein. Its TRV250 is a small molecule G protein biased ligand of the d-opioid receptor in preclinical development. Its TRV734 is a small molecule Mu-GPS that it has discovered and has developed through Phase I as a first-line, orally administered compound for the treatment of moderate to severe acute and chronic pain. Its TRV027 is a peptide b-arrestin biased ligand that targets the angiotensin II type 1 receptor (AT1R). In addition to these three product candidates, the Company has identified and has completed the Phase I program for TRV734.