PROTEOSTASIS THERAPEUTICS, INC. (NASDAQ:PTI) Files An 8-K Entry into a Material Definitive AgreementItem 1.01
PROTEOSTASIS THERAPEUTICS, INC. ExhibitEX-1.1 2 d511932dex11.htm EX-1.1 EX-1.1 Exhibit 1.1 Proteostasis Therapeutics,…To view the full exhibit click here
About PROTEOSTASIS THERAPEUTICS, INC. (NASDAQ:PTI)
Proteostasis Therapeutics, Inc. is a biopharmaceutical company. The Company is engaged in discovery and development of therapeutics that treat diseases caused by an imbalance in the proteostasis network, a set of pathways that control protein biosynthesis, folding, trafficking and clearance. It has developed the Disease Relevant Translation (DRT) technology platform, a drug screening approach for identifying highly translatable therapeutics based on predictive and functionally pertinent phenotypic assays and disease relevant models. Using this platform, it has identified a new class of small molecules, amplifiers that modulate proteins in the proteostasis network. It is developing and intend to commercialize its lead amplifier of CFTR protein, PTI-428, to improve CFTR protein function. It also focuses on developing PTI-NC-733, PTI-130, Usp14 program and unfolded protein response (UPR) program. PTI-130 is a small molecule amplifier.