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MADRIGAL PHARMACEUTICALS,INC. (NASDAQ:MDGL) Files An 8-K Entry into a Material Definitive Agreement

MADRIGAL PHARMACEUTICALS,INC. (NASDAQ:MDGL) Files An 8-K Entry into a Material Definitive AgreementItem 1.01Entry into a Material Definitive Agreement.

On December18, 2017, Madrigal Pharmaceuticals,Inc. (the “Company”) entered into an underwriting agreement (the “Underwriting Agreement”) with Goldman Sachs& Co. LLC, as representative of the several underwriters named therein (the “Underwriters”), relating to an underwritten public offering (the “Offering”) of 1,731,929shares (the “Shares”) of the Company’s common stock, par value $0.0001 per share (the “Common Stock”), which includes 225,904 shares of the Common Stock purchased by the Underwriters to a 30-day option to purchase such additional shares granted therein, at a public offering price of $83.00 per share. Subject to the terms and conditions contained in the Underwriting Agreement, the Underwriters have agreed to purchase, and the Company has agreed to sell, the Shares at a price of $78.02 per share. The net proceeds to the Company from the Offering, after deducting the Underwriters’ discount and other estimated offering expenses payable by the Company, are expected to be approximately $135 million. The net proceeds from the Offering will be used for general corporate purposes, including, without limitation, research and development expenditures, clinical trial expenditures, manufacture and supply of drug substance and drug products, acquisitions of new technologies, capital expenditures and working capital.

The Offering is expected to close on or about December21, 2017, subject to customary closing conditions.

The Underwriting Agreement contains customary representations, warranties and agreements by the Company, conditions to closing, indemnification obligations of the Company and the Underwriters, including for liabilities under the Securities Act of 1933, as amended, other obligations of the parties and termination provisions. The representations, warranties and covenants contained in the Underwriting Agreement were made only for purposes of such agreement and as of specific dates, were solely for the benefit of the parties to such agreement and may be subject to limitations agreed upon by the contracting parties.

A copy of theform of Underwriting Agreement is attached to this Current Report on Form8-K (“Current Report”) as Exhibit1.1, and is incorporated herein by reference. The foregoing is only a brief description of the material terms of the Underwriting Agreement, does not purport to be a complete description of the rights and obligations of the parties thereunder, and is qualified in its entirety by reference to Exhibit1.1.

The Company offered and is selling the above-described securities to aprospectusdated October16, 2015 and a prospectus supplementdated December18, 2017, in connection with a takedown from the Company’s shelf registration statement onFormS-3(File No.333-206135), previously declared effective by the Securities and Exchange Commission.

The legal opinion of Stradling Yocca Carlson& Rauth, P.C. relating to the Offering is filed as Exhibit5.1 to this Current Report on Form8-K.

Item 1.01 Financial Statements and Exhibits

(d) Exhibits.

MADRIGAL PHARMACEUTICALS, INC. ExhibitEX-1.1 2 a17-28424_4ex1d1.htm EX-1.1 Exhibit 1.1   Execution Version   MADRIGAL PHARMACEUTICALS,…To view the full exhibit click here
About MADRIGAL PHARMACEUTICALS,INC. (NASDAQ:MDGL)
Madrigal Pharmaceuticals, Inc., formerly Synta Pharmaceuticals Corp., is a clinical-stage biopharmaceutical company. The Company focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular-metabolic diseases and nonalcoholic steatohepatitis (NASH). The Company’s lead product, MGL-3196, is a Phase II-ready once-daily, oral, liver-directed selective thyroid hormone receptor-b (THR-b) agonist for the treatment of NASH, and heterozygous and homozygous familial hypercholesterolemia (FH). Its product pipeline also includes MGL-3745, which is used in the treatment of NASH and FH. MGL-3196 has completed Phase I single and multiple dose trials in healthy volunteers. MGL-3196 is being developed for dyslipidemia/hypercholesterolemia to lower low-density lipoproteins cholesterol, triglyceride levels and lipoprotein(a). MGL-3196 also reduces triglycerides in the plasma and liver by increasing fat metabolism and shows an anti-diabetic action.

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